2009
DOI: 10.1097/ccm.0b013e3181959864
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Influence of increased intra-abdominal pressure on fluid responsiveness predicted by pulse pressure variation and stroke volume variation in a porcine model*

Abstract: : In this animal model PPV and GEDV proved to be sensitive and specific predictors of fluid responsiveness even during increased IAP.

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Cited by 109 publications
(80 citation statements)
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References 39 publications
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“…71 Consequently, PP can increase SVV, PPV, and SPV independently of changes in blood volume. 50,72 Does this mean, however, that the dynamic variables are less useful or that we can keep the indices but raise the threshold?…”
Section: Fluid Management In Laparoscopic Surgerymentioning
confidence: 99%
See 1 more Smart Citation
“…71 Consequently, PP can increase SVV, PPV, and SPV independently of changes in blood volume. 50,72 Does this mean, however, that the dynamic variables are less useful or that we can keep the indices but raise the threshold?…”
Section: Fluid Management In Laparoscopic Surgerymentioning
confidence: 99%
“…72 The ability of SVV to measure fluid responsiveness remained until the IAP was raised above 25 mmHg when it was abolished.…”
Section: Fluid Management In Laparoscopic Surgerymentioning
confidence: 99%
“…As these dynamic indices predict respondents with more accuracy than CVP and as no CVP threshold value is reliable to diagnose fluid responsiveness, there is less need for invasive lines merely for the purpose of monitoring [19,22]. In several studies comparing PPV and SVV, PPV appears to be the most sensitive and specific variable [19,20,23].…”
Section: Individualized Gdftmentioning
confidence: 99%
“…The technique relies on cardiopulmonary interactions, and therefore any change in tidal volume and/or intrathoracic pressure will affect the interaction. Raised intra-abdominal pressure will cause higher intrathoracic pressures and an exaggerated cardiopulmonary interaction that will raise the threshold for volume responsiveness independent of preload [23]. Only PPV has been validated in this situation, and the clinician needs to understand the physiology and look for the response to a fluid challenge to individualize the threshold for fluid responsiveness [23].…”
Section: Individualized Gdftmentioning
confidence: 99%
See 1 more Smart Citation