Influence of insomnia and emotional disorders on the development of cognitive impairment in patients with chronic brain ischemia and arterial hypertension

Abstract

Aim. To study correlation between sleep disorders, cognitive impairment and emotional state in patients suffering from chronic brain ischemia and artreial hypertension. 
 Methods. The study included 65 patients of Kazan City clinical hospital №7: 35 males and 30 females aged 21 to 92. Self-Administered Gerocognitive Exam test, Spielberg-Hanin scale, questionnaire developed by the authors, Pittsburgh sleep quality assessment were used. 
 Results. It was shown that reduced sleep quality in patients with chronic brain ischemia is associated with worsening cognitive impairment. Among responders with poor subjective sleep quality only 21% had cognitive function within normal limits, while in 88% of patients with good subjective sleep quality cognitive function was normal. High level of anxiety was found to cause poor sleep quality. 57% of patients were diagnosed with high level of situational anxiety combined with poor subjective sleep quality and among patients with good sleep quality in only 12% of responders high level of situational anxiety was found. In patients increase of the level of anxiety is associated with more frequent cognitive impairment. Only 38% of patients with high level of anxiety had normal cognitive function compared to 85% of responders with low level of anxiety and normal function. 
 Conclusion. Sleep quality and level of anxiety influence the development of cognitive disorders in patients with chronic brain ischemia.