Influence of ionic liquids’ nature on chromatographic retention of benzimidazoles by RP HPLC

Yadrova, Anastasiya A.; Grinevich, Oksana I.; Шафигулин, Р. В.; Буланова, А. В.

doi:10.1080/10826076.2020.1858315

Cited by 6 publications

(2 citation statements)

References 32 publications

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“…They are nonvolatile and nonflammable and have excellent chemical and thermal stability (David & Moldoveanu, 2022). When these ionic liquids were added to the mobile phase as additives, the retention time was found to decrease and also the resolution was improved (Yadrova et al, 2021; Zhang et al, 2003). The effects of different ionic liquids at different concentrations were also studied.…”

Section: Effect Of Ionic Liquids As Mobile Phase Additivesmentioning

confidence: 99%

Retention behaviour of analytes in reversed‐phase high‐performance liquid chromatography—A review

V.¹,

Basuri²,

Sahini³

et al. 2022

Biomedical Chromatography

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The understanding of principles that drive the separation in reversed‐phase chromatography plays an important role in the prediction of the elution of solutes in RP‐HPLC. The separation in RP‐HPLC is based on the principle of adsorption and partition. In addition, the logP value, the pKa value of the drug and chromatographic parameters like mobile phase pH, buffer concentration, organic modifier and mobile phase additives also influence the retention and selectivity of the analyte. It was found that hydrophobic, electrostatic, hydrogen bonding and other specific interactions between the stationary phase and the solutes, along with the hydrophobicity of an analyte molecule (logP), modify the retention behaviour of the analytes. This article gives special attention to the influence of ionization and ion interaction on the separation of analytes. The drug molecules with different logP values containing protonated and deprotonated acids, bases and zwitterions are selected as examples and this article addresses various issues related to the method development, relationships between analyte retention and mobile phase pH and the pKa value of the analyte. The advances in this regard, with highlights on topics such as mechanisms of retention and various factors that influence the retention behaviour of analytes, are also updated with suitable examples.

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Section: Effect Of Ionic Liquids As Mobile Phase Additivesmentioning

confidence: 99%

Retention behaviour of analytes in reversed‐phase high‐performance liquid chromatography—A review

V.¹,

Basuri²,

Sahini³

et al. 2022

Biomedical Chromatography

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show abstract

“…The hydrogenation reaction was run at a hydrogen pressure of 2 atm and T = 423-493 K. A hydrogen/hydrocarbon molar ratio in the reactor was kept around 18. For more details of our chromatographic experiments, see [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Hydrogenation of Xylenes, Ethylbenzene, and Isopropylbenzene on Ni Nanoparticles

Шафигулин

Буланова

Кузнецов

et al. 2022

Int. J Self-Propag. High-Temp. Synth.

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Kinetic and thermodynamic parameters of the catalysts containing 15% of the Ni nanoparticles prepared by levitation-jet method in hydrogenation of xylenes, ethylbenzene, and isopropylbenzene were studied using a laboratory-made chromatographic setup. At relatively low hydrogen pressure (2 atm) and temperatures of 423-493 K, our catalysts provide a high extent of conversion of the compounds studied and selectivity with respect to p-xylene.

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Reversed-phase HPLC

Moldoveanu

David

2022

Essentials in Modern HPLC Separations

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Influence of ionic liquids’ nature on chromatographic retention of benzimidazoles by RP HPLC

Cited by 6 publications

References 32 publications

Retention behaviour of analytes in reversed‐phase high‐performance liquid chromatography—A review

Retention behaviour of analytes in reversed‐phase high‐performance liquid chromatography—A review

Hydrogenation of Xylenes, Ethylbenzene, and Isopropylbenzene on Ni Nanoparticles

Reversed-phase HPLC

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