Influence of laser photocoagulation for clinically significant diabetic macular oedema (DMO) on short-wavelength and conventional automated perimetry

Restoration of Retinal Structure and Function after Selective Photocoagulation

“…Although pan-retinal photocoagulation is a highly effective approach to halting angiogenesis, it results in permanent retinal scarring and decreased peripheral, color, and night vision ( Higgins et al, 1986;Shimura et al, 2005). Focal and grid laser photocoagulation is an effective treatment of macular edema, but also causes scotomata and scarring (Morgan and Schatz, 1989;Schatz et al, 1991;Early Treatment Diabetic Retinopathy Study Research Group, 1995).…”

“…Focal and grid laser photocoagulation is an effective treatment of macular edema, but also causes scotomata and scarring (Morgan and Schatz, 1989;Schatz et al, 1991;Early Treatment Diabetic Retinopathy Study Research Group, 1995). Laser burns can enlarge postoperatively and cause choroidal neovascularization (Lewen, 1988;Lewis et al, 1990), subretinal fibrosis (Guyer et al, 1992;Rutledge et al, 1993;Lövestam-Adrian and Agardh, 2000), and additional visual field loss (Striph et al, 1988;Hudson et al, 1998;Ishiko et al, 1998;Mainster, 1999;Sinclair et al, 1999). Over time, loss of one class of retinal cells may, by trans-synaptic degeneration and associated inflammation, result in the loss of other retinal neurons (Stone, 1950;Birnbach et al, 1994) and RPE remodeling (Framme et al, 2009) or retinal remodeling (Marc et al, 2007).…”

The relationship between visual function, duration and main causes of vision loss and falls in older people with low vision

“…Visual field loss was measured based on the number of abnormal stimulus locations, defined as those with statistical probability levels of p<0.05. A pattern deviation plot was used to determine the number of affected points [28].…”

Statistical modelling of the central 10-degree visual field in short-wavelength automated perimetry

“…A number of studies have reported deficits in the SWS pathway in macular eye disease which also precede deficits in the achromatic pathway [1,8,9,10,11,20,21,33,45]. The short-wavelength perimetric sensitivity profile of the hill of vision in the central visual field is flatter than the 30-deg visual field and yields lesser between-subject variability than the peripheral stimulus locations [43].…”