Modern lithographic simulation engines 1 are quite capable of determining the detrimental impact of source and lens aberrations on low k1 lithographic metrics -given the proper input 2 . Circuit designers, lithographic engineers, and manufacturing facilities would seem to be the beneficiaries of the predictive power of lithographic simulators; however, in-situ methods for accurately determining lens aberrations and source metrology maps have only rather recently been accepted 3 and integrated into practice 4 . For this work, we introduce several new methods for characterizing scanner performance including a high accuracy source metrology tool and integrated simulation engine 5 . We focus attention on the combined detrimental effects of lens aberrations, source non-ideality, distortion, synchronization error, and transmission error on deep sub-wavelength lithographic metrics such as: H-V bias, feature-shift, and ∆CD. After a brief theoretical discussion, we describe a matrix of simulation case studies and present results. Finally, we discuss potential applications for the simulation performance framework and its potential impact to industry.