Influence of lung collapse distribution on the physiologic response to recruitment maneuvers during noninvasive continuous positive airway pressure

Abstract

Compared to n-CPAP, n-CPAP(SIGH) further improved arterial oxygenation in B(L) patients, whereas it produced no additional benefit in those with U(L).

The Integrative Role of the Sigh in Psychology, Physiology, Pathology, and Neurobiology

“…Under certain conditions, the sigh can become uncoupled and independent from eupneic activity (Lieske et al, 2000). Sighs have important ventilatory functions as they lead to a maximal expansion of the lungs, which prevents the progressive collapse of alveoli (atelectasis) (Bendixen et al, 1964; Cammarota et al, 2011; Hess and Bigatello, 2002; Hoch et al, 1998; Koch et al, 2012). Sighs also restore lung compliance (Caro et al, 1960; Ferris and Pollard, 1960) and maintain normal lung function (Cherniack et al, 1981).…”

Year in review in Intensive Care Medicine 2011: III. ARDS and ECMO, weaning, mechanical ventilation, noninvasive ventilation, pediatrics and miscellanea

“…Cammarota et al [36] compared different regimes of non-invasive ventilatory support by a Venturi mask or by CPAP in patients with hypoxemic respiratory failure due to either unilateral or bilateral lung involvement. The authors found that CPAP with a pressure of 10 cmH 2 O was better in oxygenating blood than breathing with a Venturi mask and also normalized PaCO 2 in patients with bilateral affection.…”

Helmet CPAP Versus Oxygen Therapy in Hypoxemic Acute Respiratory Failure: A Meta-analysis of Randomized Controlled Trials

“…In Europe, oral-nasal masks are the most commonly used interface for NIV; 7 however, the helmet interface has gained wide acceptance in some countries, such as Italy, as a more comfortable interface for patients with hARF. 7 Several studies have evaluated the efficacy of helmet CPAP for hARF, [8][9][10][11][12] and most have found that helmet CPAP significantly reduced the intubation rate and mortality while improving clinical outcomes compared to standard oxygen therapy. However, a robust conclusion has not been reached on the utility of helmet CPAP owing to the small sample size in current RCTs.…”