Abstract. In this study we investigated the fatigue life and crack growth behavior of Al-5183 alloy. Microscopic analysis revealed nearly equi-axed grains and no texture in longitudinal or cross-sectional plane of the welded plates. Gas porosities with an average size of 45 μm, comparable to grain size (55 μm), were present and often initiate fatigue failures. Load-controlled cyclic tests at different stress-ratios (R = -1, -0.5, 0.1, 0.5. 0.7 and 0.8) revealed decrease in fatigue lives with increase in R-ratio. At R > 0.7, no fatigue failure could be observed, suggesting a probable mean-stress saturation effect on fatigue. Mean stress also tends to control the crack initiation sites: surface initiated failures at low mean stresses while sub-surface pores induced failures at higher mean stresses. Fatigue-crack growth tests on CT specimens at different R-ratios (0.1, 0.5 and 0.8) revealed reduction in crack growth rates (and in threshold values) with increasing R-ratio. The ∆K applied for pores responsible for fatigue failures were often lower than or near to the threshold values and also, the size of such pores was of order of magnitude of grain size, thus crack initiated from pores are short cracks and further tests are progress.