Influence of melatonin on pubertal development in male deer mice (Peromyscus maniculatus)

Whitsett, J. Mal; Underwood, Herbert; Cherry, James A.

doi:10.1530/jrf.0.0720287

Cited by 5 publications

(1 citation statement)

References 23 publications

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“…Otra fuente de variación en la respuesta al fotoperiodo, que se ha observado, es la experiencia. Pues los estudios realizados por Horton (1984) y Whitsett et al (1984) sugieren que la longitud del día crítico en la cual un individuo responde, no se hereda de manera inmutable, sino que depende del grado de su experiencia. De una o de otra forma, la flexibilidad, tanto genética como experiencial, parecen ser la característica propia de las estrategias reproductoras de los pequeños roedores de vida corta.…”

Section: Fotoperiodounclassified

Estudio sobre algunos aspectos de la biología de la reproducción de Peromyscus winkelmanni

Lorenzana

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Section: Fotoperiodounclassified

Estudio sobre algunos aspectos de la biología de la reproducción de Peromyscus winkelmanni

Lorenzana

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Influence of Photoperiod, Ambient Temperature and Melatonin on Testosterone Synthesis and Release During Reproductive Maturation in Male Deer Mice

Fail

Whitsett

1988

Journal of Andrology

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Four experiments were designed to investigate the influence of photoperiod and other environmental factors on androgen production and reproductive maturation in deer mice. Male prairie deer mice (Peromyscus maniculatus), born in a light/dark cycle of 6L:18D, either remained in this short photoperiod or were switched to a long day regimen of 16L:8D at weaning. In a cross-sectional experiment, the deer mice were killed between 3 and 8 weeks of age for measurement of serum testosterone concentration and reproductive organ weights. In a second experiment, blood was collected from each mouse at weekly intervals between 3 and 9 weeks of age. This repeated measures design was used to reduce the high variability in testosterone values observed in the first experiment. Reproductive organs were weighed at the termination of the experiment. Testosterone concentrations and reproductive organ weights were greater in males reared in the long photoperiod in both experiments. In a third experiment, the animals were housed under five different conditions to test the influence of high ambient temperature and melatonin as well as photoperiod. At 7 weeks of age, they received an injection of hCG or saline. More testosterone was released in deer mice reared in 16L:8D and 27 C than in those reared in short days (6L:18D) or those reared in high ambient temperature (35 C) or those treated with exogenous melatonin. One week later, animals were sacrificed. The single hCG treatment caused significant reversal of the suppression of accessory sex organ weights following melatonin, short days or 35 C temperature. In a fourth experiment, the additive influence of melatonin and 35 C temperature was tested. Animals treated with 35 C or both melatonin and 35 C had lower serum testosterone at 7 weeks of age, released less testosterone after hCG, and had smaller organ weights with or without hCG than long day controls. The influence of melatonin treatment and 35 C temperature appears to be additive for testicular weight and testosterone release after hCG. Thus, the attenuation of reproductive development that accompanied short days, melatonin treatment and high ambient temperature occurred via diminished testosterone secretion, which can be overcome at least in part by gonadotropin treatment.

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Endocrinology of Sika Deer

Yamauchi

Matsuura

Sika Deer

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Influence of melatonin on pubertal development in male deer mice (Peromyscus maniculatus)

Cited by 5 publications

References 23 publications

Estudio sobre algunos aspectos de la biología de la reproducción de Peromyscus winkelmanni

Estudio sobre algunos aspectos de la biología de la reproducción de Peromyscus winkelmanni

Influence of Photoperiod, Ambient Temperature and Melatonin on Testosterone Synthesis and Release During Reproductive Maturation in Male Deer Mice

Endocrinology of Sika Deer

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