Influence of menopausal status on diagnostic accuracy of myometrial invasion in endometrial cancer: diffusion-weighted and dynamic contrast-enhanced MRI at 3 T

Diagnostic accuracy of 3.0T diffusion‐weighted MRI for patients with uterine carcinosarcoma: Assessment of tumor extent and lymphatic metastasis

“…One of the study limitations was the retrospective nature because of the low incidence of carcinosarcoma. Nonetheless, the MR acquisition protocol was consistent throughout the study period because of ongoing prospective studies for endometrial cancer . Second, the number of patients was low, which is understandable given the rarity of the tumor.…”

“…Enrolled patients were imaged with a 3T MR system (Tim Trio, Siemens, Erlangen, Germany). The lower nine elements of the integrated spine coil and the lower six elements of the body‐phased array coil were used to cover the entire pelvis . In brief, DW MRI was performed using the single‐shot echo‐planar technique with fat suppression (repetition time / echo time [TR/TE], 3300/79 msec; number of signal averages, 4; section thickness, 4 mm; gap, 1 mm; matrix, 128 × 128; field of view (FOV), 20 × 20 cm).…”

Current Status of Magnetic Resonance Imaging in Patients with Malignant Uterine Neoplasms: A Review

“…The myometrial-endometrial interfaces on T2WI may be obscure in postmenopausal women due to hormone-related atrophy and fibrous involution of the uterine smooth muscle tissue. In premenopausal patients with EC planning to undergo fertility-preserving treatment, DCE-MRI is superior to DWI in terms of excluding the possibility of the myometrial invasion (65).…”

Developing and validating a multivariable prediction model to improve the diagnostic accuracy in determination of cervical versus endometrial origin of uterine adenocarcinomas: A prospective MR study combining diffusion‐weighted imaging and spectroscopy

“…9 The absence of deep myometrial invasion reported by Haider et al 10 was not a significant indicator by logistic regression in this study. 21 In the endometrial cancer, ADC was significantly higher in the well/moderately differentiated tumors compared with poorly differentiated tumors at 3T (1.04 vs. 0.81 3 10 23 mm 2 /s) 26 or at 1.5T (0.92-0.93 vs. 0.73 3 10 23 mm 2 /s). Moreover, T1-weighted dynamic-enhanced sequences aid in making the diagnosis and may help in appropriate treatment planning of these patients.…”

“…[23][24][25] Based on the histological correlation, ADC value was found to correlate negatively with cellular density. 21 In the endometrial cancer, ADC was significantly higher in the well/moderately differentiated tumors compared with poorly differentiated tumors at 3T (1.04 vs. 0.81 3 10 23 mm 2 /s) 26 or at 1.5T (0.92-0.93 vs. 0.73 3 10 23 mm 2 /s). 27 Our data showed that the ADC values of adeno-/adenosquamous carcinomas from cervix were significantly higher than that from the endometrium, regardless of tumor differentiations.…”