“…In the past, investigators have attempted to address this issue. For instance, experimental studies suggested that the micro-damage accumulation in bone play a significant role in its post-yield behavior (Akkus and Rimnac, 2001;Burr et al, 1997Burr et al, ,1998Forwood and Parker, 1989;Norman et al, 1998;Reilly and Currey, 1999;Timlin et al, 2000;Zioupos et al, 1994). Also, it has been shown that yielding of bone tissues coincides with the formation of diffuse damages (Zioupos et al, 1994), and microcracking may help sustain the toughness of bone (Vashishth et al, 2000(Vashishth et al, ,2003Zioupos, 2001).…”