Influence of Nutrient Intake on 24 Hour Urinary Hydration Biomarkers Using a Clustering-Based Approach

Adams, William M.; Wininger, Michael; Zaplatosch, Mitchell E.; Hevel, Derek J.; Maher, Jaclyn P.; McGuirt, Jared T.

doi:10.3390/nu12102933

Cited by 2 publications

(1 citation statement)

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“…Regarding the quantity of solutes, the most important ones are sodium, potassium and urea. In physiological conditions, their amounts depend mainly on diet because osmole elimination in urine is closely related to daily osmole intake and, in particular, daily protein intake [ 58 ], but also to calcium, magnesium and sugar consumption [ 59 ].…”

Section: Laboratory Methodsmentioning

confidence: 99%

How to Monitor Hydration Status and Urine Dilution in Patients with Nephrolithiasis

et al. 2023

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Maintenance of hydration status requires a tight balance between fluid input and output. An increase in water loss or a decrease in fluid intake is responsible for dehydration status, leading to kidney water reabsorption. Thus, urine volume decreases and concentration of the different solutes increases. Urine dilution is the main recommendation to prevent kidney stone recurrence. Monitoring hydration status and urine dilution is key to preventing stone recurrence. This monitoring could either be performed via spot urine or 24 h urine collection with corresponding interpretation criteria. In laboratory conditions, urine osmolality measurement is the best tool to evaluate urine dilution, with less interference than urine-specific gravity measurement. However, this evaluation is only available during time lab examination. To improve urine dilution in nephrolithiasis patients in daily life, such monitoring should also be available at home. Urine color is of poor interest, but reagent strips with urine-specific gravity estimation are currently the only available tool, even with well-known interferences. Finally, at home, fluid intake monitoring could be an alternative to urine dilution monitoring. Eventually, the use of a connected device seems to be the most promising solution.

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Section: Laboratory Methodsmentioning

confidence: 99%

How to Monitor Hydration Status and Urine Dilution in Patients with Nephrolithiasis

et al. 2023

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D-Pinitol—Active Natural Product from Carob with Notable Insulin Regulation

Azab¹

2022

Nutrients

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Carob is one of the major food trees for peoples of the Mediterranean basin, but it has also been traditionally used for medicinal purposes. Carob contains many nutrients and active natural products, and D-Pinitol is clearly one of the most important of these. D-Pinitol has been reported in dozens of scientific publications and its very diverse medicinal properties are still being studied. Presently, more than thirty medicinal activities of D-Pinitol have been reported. Among these, many publications have reported the strong activities of D-Pinitol as a natural antidiabetic and insulin regulator, but also as an active anti-Alzheimer, anticancer, antioxidant, and anti-inflammatory, and is also immune- and hepato-protective. In this review, we will present a brief introduction of the nutritional and medicinal importance of Carob, both traditionally and as found by modern research. In the introduction, we will present Carob’s major active natural products. The structures of inositols will be presented with a brief literature summary of their medicinal activities, with special attention to those inositols in Carob, as well as D-Pinitol’s chemical structure and its medicinal and other properties. D-Pinitol antidiabetic and insulin regulation activities will be extensively presented, including its proposed mechanism of action. Finally, a discussion followed by the conclusions and future vision will summarize this article.

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Influence of Nutrient Intake on 24 Hour Urinary Hydration Biomarkers Using a Clustering-Based Approach

Cited by 2 publications

References 73 publications

How to Monitor Hydration Status and Urine Dilution in Patients with Nephrolithiasis

How to Monitor Hydration Status and Urine Dilution in Patients with Nephrolithiasis

D-Pinitol—Active Natural Product from Carob with Notable Insulin Regulation

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