Classroom discussion, despite its association with good academic outcomes, is exceedingly rare in U.S. schools. The Word Generation intervention involves the provision of texts and activities to be implemented across content area class, organized around engaging and discussable dilemmas. The program was evaluated with 1,554 middle grade students in 28 schools randomly assigned to treatment or control conditions. There were large effects on classroom discussion quality across all content areas, especially in math and science (Cohen's d = 0.38-1.13). The program also produced JOSHUA F. LAWRENCE is assistant professor at the University of California, Irvine, 3200 Education Building, Irvine, CA 92697; e-mail: jflawren@uci.edu. His research focuses on understanding and improving literacy development and educational outcomes of students at risk, including language minority students. AMY C. CROSSON is a research associate at the Learning Research and Development Center, University of Pittsburgh. She studies literacy interventions to support comprehension, academic writing, and academically productive classroom talk for linguistically diverse students in underresourced schools. E. JULIANA PARÉ-BLAGOEV is senior research scientist at George Washington University and director of the Center for Applied Developmental Science and Neuroeducation in the Special Education and Disabilities Program. She works at the intersection of neuroscience, developmental psychology, and education to bridge research and practice. CATHERINE E. SNOW is the Patricia Albjerg Graham Professor at the Harvard Graduate School of Education. She studies language and literacy development in children from birth through adolescence, with particular focus on children at educational risk because of socioeconomic or immigrant status, limited English skills, and/or inadequate schooling opportunities.