Influence of phenolic profile on the RP-HPLC detection and anti-carcinogenic potential of cherry laurel extracts from Black Sea Region-Turkey

Chemistry and biochemistry of dietary carotenoids: bioaccessibility, bioavailability and bioactivities

“…Four anthocyanins have been reported in cherry laurel (Table 4). Keracyanin chloride was the most abundant anthocyanins, as reported in a a recent study (Bayrambaş et al, 2019). Besides, cyanidin-3-glucoside, cyanidin-3-rutinoside, and pelargonidin-3-glucoside were also detected in cherry laurel (Karahalil and Şahin, 2011).…”

“…Chlorogenic acid is the most abundant phenolic acid, followed by caffeic, pcoumaric, syringic, and gallic acids. Besides, o-coumaric, ferulic, p-hydroxybenzoic, protocatechuic, protocatechuic acid ethyl ester, and vanillic acids are also present (Alasalvar et al, 2005;Karahalil & Şahin, 2011;Karabegović et al, 2014;Ozturk et al, 2017;Bayrambaş et al, 2019). Ayaz et al (1997) reported the presence of protocatechuic, p-hydroxybenzoic, vanillic, caffeic, and p-coumaric acids in several cultivated and wild cherry laurel varieties where vanillic acid was the most abundant phenolic acid.…”

“…Besides, kaempferol was the most abundant flavonols detected in cherry laurel, followed by quercetin-3-glucoside and rutin. Cherry laurel also contains procyanidin B2 (14.4-52.5 mg/100 g fw) (Bayrambaş et al, 2019). Figure 1 shows chemical structures of the phenols and polyphenols present in cherry laurel.…”

“…Since cherry laurel has high contents of phenolic acids, anthocyanins, and flavan-3-ols, it is able to provide health benefits beyond basic nutrition (Karahalil and Şahin, 2011;Bayrambaş et al, 2019). Cherry laurel renders beneficial effects on human health such as neuroprotective, anti-diabetic, dimethoate-induced liver damage, antioxidative stress, anti-microbial, wound healing, and cytotoxic activities (Orhan and Akkol, 2011;Orhan et al, 2015;Demir et al, 2017;Eken et al, 2017;Ayla et al, 2019;Bayrambaş et al, 2019). These health effects of cherry laurel are reviewed below.…”

“…Finally, Bayrambaş et al (2019) investigated the cytotoxic effect of methanolic extract of three cherry laurel varieties on HCT 116 human colon cancer cell line. Treatment with 61K04 variety prevented the growth of cancer cells (55% apoptosis), followed by 61K05 (27% apoptosis), and 55K06 (36.9% apoptosis) varie- Antioxidants, polyphenols, and health benefits of cherry laurel: a review Alasalvar and Chang ties.…”