Influence of physically demanding occupations on the development of osteoarthritis of the hip: a systematic review

Unverzagt, Susanne; Bolm‐Audorff, Ulrich; Frese, Thomas; Hechtl, Julia; Liebers, Falk; Moser, Konstantin; Seidler, Andreas; Weyer, Johannes; Bergmann, Andreas

doi:10.1186/s12995-022-00358-y

Cited by 9 publications

(11 citation statements)

References 47 publications

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“…There is ample epidemiologic evidence that occupations with highly physical workloads-for example, within agriculture, fishery, or forestry-involving manual labor, such as lifting and carrying heavy items, climbing stairs, or working in kneeling positions, are associated with increased risk for knee OA and hip OA [50].…”

Section: Chronic Joint Overloadingmentioning

confidence: 99%

Osteoarthritis, part of life or a curable disease? A bird's‐eye view

Englund

2023

J Intern Med

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Osteoarthritis (OA) is a chronic joint disease caused by disruption of joint homeostasis by a variety of systemic and biomechanical factors. The disease is characterized by degradation of cartilage and other joint tissues, and low‐grade inflammation which may result in pain, reduced function, and disability. The disease appears to have ancient origins, with findings of OA recognized in fossilized bones from birdlike dinosaurs living some 130 million years ago. Today, the burden of OA in the world's population is steadily increasing due to aging and often rising rates of obesity. Structural findings, indicative of the disease, are also frequent in asymptomatic persons, which make the distinction between disease and normal aging sometimes challenging. OA is frequently associated with comorbidity in the form of obesity, cardiovascular disease, and depressive symptoms. The current management and treatments largely rely on contextual factors, and the actual effects of the intended therapeutic element of today's interventions are minor. The different mechanistic pathways (endotypes) and clinical characteristics (phenotypes) of OA make the development of disease‐modifying treatments challenging. Current development of drug candidates, aimed to restore joint homeostasis, is mainly targeting either inhibition of catabolic factors or stimulation of anabolic factors. However, there is yet no breakthrough in stage III clinical trials. Earlier diagnosis, better knowledge of endotypes—for example, by new insights into soluble biomarkers, and compositional imaging—and more careful selection of patients into clinical trials are possible tools to aid development of future therapies.

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Section: Chronic Joint Overloadingmentioning

confidence: 99%

Osteoarthritis, part of life or a curable disease? A bird's‐eye view

Englund

2023

J Intern Med

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“…La exposición continua a vibraciones se relaciona con trastornos musculoesqueléticos, cuya afectación posterior genera múltiples manifestaciones articulares sobre todo en las regiones del cuerpo que tienen mayor contacto con las vibraciones (Joseph et al, 2023). Una de las patologías asociadas a alteraciones musculoesqueléticas que se presenta en mayor proporción es la artrosis de cadera, la cual determina complicaciones en deambulación y reposo, esto en dependencia de la edad y cuadro clínico no relacionado a traumatismos previos del paciente (Unverzagt et al, 2022).…”

Section: Fuente: Elaborada Por El Autorunclassified

“…Un trabajo que precisa esfuerzo físico exigente se ha relacionado con trastornos musculoesqueléticos como dolor crónico (Dalager et al, 2019), artrosis de cadera (de Gonzalez et al, 2020;Unverzagt et al, 2022), síndrome de túnel carpiano (Hassan et al, 2022) y osteoartritis de extremidades inferiores (Canetti et al, 2020).…”

Section: Fuente: Elaborada Por El Autorunclassified

Salud ocupacional: rol del personal de enfermería en la evaluación y prevención de riesgos

Hurtado¹

2023

LATAM

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La salud ocupacional en la actualidad ha cobrado un papel fundamental, posicionándose como una herramienta para la identificación de las necesidades y aumento de la calidad de vida de los trabajadores, buscando garantizar el bienestar físico, mental y social de la población en sus ambientes de trabajo. Los riesgos laborales se clasifican en físicos, mecánicos, químicos, biológicos, psicosociales y ambientales. El objetivo de esta revisión es describir los principales efectos sobre la salud por la exposición ocupacional a agentes físicos, químicos, biológicos y psicosociales. El rol de la enfermería ocupacional y las medidas de intervención en promoción de la salud y prevención de accidentes en los ambientes laborales, han generado un amplio beneficio en términos de bienestar de los trabajadores y productividad de instituciones y empresas. Se utilizó metodología con enfoque cualitativo, descriptivo y bibliográfico documental de investigaciones realizadas en función a la temática del estudio; entre los resultados obtenidos, se evidenció que la prevalencia e incidencia de las enfermedades ocupacionales va a depender de su ocupación o puesto laboral que ejercen. Como enfermeros se desarrollaron funciones asistenciales, administrativas, educacionales, de integración e investigación, sin embargo, el mayor número de actividades que realizan fueron las administrativas y educacionales; por lo cual es ideal que se consideren diseños en donde se aborden actividades operativas que incluyan salud física y mental del personal, lo cual va a generar un impacto positivo en los trabajadores, lo cual se refleja en el rendimiento a nivel laboral.

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“…Various studies show a positive relationship between prolonged lifting and carrying of heavy loads or physically demanding work in general, and the risk of developing HOA [ 15 – 17 ]. In a previous systematic review, we found that there is a strong association between occupational exposure to other physically demanding ergonomic risk factors, such as force exertion, tiring posture, repetitiveness, lifting, kneeling and/or squatting, and climbing, and HOA among men [ 18 ]. Although there are known differences between men and women in the prevalence of musculoskeletal disorders and pain [ 19 ], resulting healthcare use, and work disability [ 5 , 20 ], there is limited and inconsistent evidence linking occupational exposures to HOA [ 13 , 21 , 22 ].…”

Section: Introductionmentioning

confidence: 99%

Physically demanding occupations among females and sex-related differences to develop osteoarthritis of the hip: a systematic review and meta-analysis

Unverzagt,

Bergmann,

Denny

et al. 2024

J Occup Med Toxicol

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Background Hip osteoarthritis (HOA) is a leading cause of disability increasing with age and is more prevalent in women and in various physically demanding occupations. This systematic review identifies and summarises occupational exposures for women in physically demanding occupations and discusses sex differences and consequences. Methods In this systematic review, we searched various electronic databases for reports published between date of database inception and October 2022. We included cohort studies and case-control studies that assessed the association between exposure to physically demanding occupations and the development of HOA. We then assessed the methodological quality of selected studies, extracted relative effects, compared the risk for women and men and meta-analytically reviewed the effects of physically demanding occupations. All steps were based on a study protocol published in PROSPERO (CRD42015016894). Results We included six cohort studies and two case-control studies in this systematic review. These studies showed a considerably increased risk of developing HOA in both sexes. Women working in traditionally female-dominated occupations such as cleaning, sales, catering, childcare and hairdressing that are physically demanding, have a higher risk of developing HOA than men in similarly physically demanding occupations. Conversely, in traditionally male-dominated occupations with a high heterogeneity of work activities, such as agriculture, crafts, construction, as well as in low-skilled occupations, the risk was higher for men. One exception are health occupations, which are grouped together with a wide range of other technical occupations, making it difficult to draw conclusions. Conclusions Existing studies indicate an association between various occupations with a high physical workload and an increased risk of developing HOA. Occupational prevention and individual health promotion strategies should focus on reducing the effects of heavy physical workloads at work. The aforementioned as well as early detection should be specifically offered to women in female-dominated occupations and to people working in elementary occupations.

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Influence of physically demanding occupations on the development of osteoarthritis of the hip: a systematic review

Cited by 9 publications

References 47 publications

Osteoarthritis, part of life or a curable disease? A bird's‐eye view

Osteoarthritis, part of life or a curable disease? A bird's‐eye view

Salud ocupacional: rol del personal de enfermería en la evaluación y prevención de riesgos

Physically demanding occupations among females and sex-related differences to develop osteoarthritis of the hip: a systematic review and meta-analysis

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