Influence of Platelet Concentrates on Postextraction Socket Healing: A Literature Review

Patil, Shankargouda; Pawar, Vivek; Khurshid, Zohaib; Almasri, Mazen; Rudrappa, Sheetal Kumar; B, Prem Karthick; Beshir, Saiid Elshafey M; Mokli, Lujain K

doi:10.5005/jp-journals-10015-1899

Cited by 2 publications

(1 citation statement)

References 45 publications

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“…PRP mainly includes platelets, and leukocytes are eliminated during its preparation [7]. The process requires two centrifugation steps and adhesion substances such as thrombin, an anticoagulant, or calcium chloride, which may produce antibodies, such as factors 6 and 9, posing a life-threatening risk to patients with coagulopathies [8,9].…”

Section: Introductionmentioning

confidence: 99%

Imaging Evaluation of Platelet-Rich Fibrin in Post-Exodontic Bone Regeneration: A Systematic Review

Molina-Barahona,

Delgado-Gaete,

Morales-Navarro

et al. 2023

Dentistry Journal

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Tooth extraction is the most common procedure in dental practice. However, in the long term, it may cause alveolar ridge atrophy. This systematic review aimed to evaluate the role of platelet-rich fibrin (PRF) in post-exodontic alveolar ridge preservation in terms of its effectiveness in the regeneration of bone tissue as assessed by imaging and its efficacy compared to physiological bone healing. The study is presented in accordance with the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. This systematic review was conducted using electronic databases such as PubMed, Scopus, Web of Science, and Science Direct. The gray literature search was conducted in the New York Academy of Medicine Grey Literature Report. All the studies in this systematic review were randomized controlled trials (RCTs). The risk of bias was performed according to the Cochrane Handbook for Systematic Reviews of Interventions 6.2 (RevMan 6.2). Considering the inclusion and exclusion criteria, we included 17 randomized clinical trials published up to 2022 investigating the efficacy of PRF in post-exodontic bone regeneration. Based on the results of clinical studies, it can be stated that despite not being statistically significant, PRF promotes neoformation and prevents bone loss between three and four months post-extraction.

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Section: Introductionmentioning

confidence: 99%

Imaging Evaluation of Platelet-Rich Fibrin in Post-Exodontic Bone Regeneration: A Systematic Review

Molina-Barahona,

Delgado-Gaete,

Morales-Navarro

et al. 2023

Dentistry Journal

View full text Add to dashboard Cite

show abstract

Imaging Evaluation of Platelet-Rich Fibrin in Post-Exodontic Bone Regeneration: A Systematic Review

Molina-Barahona,

Delgado-Gaete,

Morales-Navarro

et al. 2023

Preprint

View full text Add to dashboard Cite

Tooth extraction is the most common procedure in dental practice. However, in the long term, it may cause alveolar ridge atrophy. This systematic review aimed to evaluate the role of platelet-rich fibrin (PRF) in post-exodontic alveolar ridge preservation in terms of its effectiveness in the regeneration of bone tissue as assessed by imaging and its efficacy compared to physiological bone healing. The study is presented in accordance with the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. This systematic review was conducted using electronic databases such as PubMed, Scopus, Web of Science, and Science Direct. The grey literature search was conducted in the New York Academy of Medicine Grey Literature Report. All the studies in this systematic review were randomized controlled trials (RCTs). The risk of bias was performed according to the Cochrane Handbook for Systematic Reviews of Interventions 6.2 (RevMan 6.2). Considering the inclusion and exclusion criteria, we included 17 randomized clinical trials, published up to 2022 investigating the efficacy of PRF in post-exodontic bone regeneration. Based on the results of clinical studies, it can be stated that despite not being statistically significant, PRF promotes neoformation and prevents bone loss between three and four months post-extraction.

show abstract

Influence of Platelet Concentrates on Postextraction Socket Healing: A Literature Review

Cited by 2 publications

References 45 publications

Imaging Evaluation of Platelet-Rich Fibrin in Post-Exodontic Bone Regeneration: A Systematic Review

Imaging Evaluation of Platelet-Rich Fibrin in Post-Exodontic Bone Regeneration: A Systematic Review

Imaging Evaluation of Platelet-Rich Fibrin in Post-Exodontic Bone Regeneration: A Systematic Review

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