Influence of Platelet-Rich Fibrin on Alveolar Ridge Preservation

Suttapreyasri, Srisurang; Leepong, Narit

doi:10.1097/scs.0b013e31828b6dc3

Cited by 103 publications

(112 citation statements)

References 24 publications

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“…However, in alveolar ridge preservation and implant therapy, most of the studies did not mention the smoking status (ridge preservation 4/8 (Hauser et al. 2013, Suttapreyasri & Leepong 2013, Kumar et al. 2015, and Yelamali & Saikrishna 2015), and implant therapy 2/3 (Boora et al.…”

Section: Resultsmentioning

confidence: 99%

Regenerative potential of leucocyte‐ and platelet‐rich fibrin. Part B: sinus floor elevation, alveolar ridge preservation and implant therapy. A systematic review

Castro

Meschi

Temmerman

et al. 2017

J Clinic Periodontology

156

133

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AimTo analyse the effect of leucocyte‐ and platelet‐rich fibrin (L‐PRF) on bone regeneration procedures and osseointegration.Materials and MethodsAn electronic and hand search was conducted in three databases (MEDLINE, EMBASE and Cochrane). Only randomized clinical trials, written in English where L‐PRF was applied in bone regeneration and implant procedures, were selected. No follow‐up restrictions were applied.ResultsA total of 14 articles were included and processed. Three subgroups were created depending on the application: sinus floor elevation (SFE), alveolar ridge preservation and implant therapy. In SFE, for a lateral window as well as for the trans‐alveolar technique, histologically faster bone healing was reported when L‐PRF was added to most common xenografts. L‐PRF alone improved the preservation of the alveolar width, resulting in less buccal bone resorption compared to natural healing. In implant therapy, better implant stability over time and less marginal bone loss were observed when L‐PRF was applied. Meta‐analyses could not be performed due to the heterogeneity of the data.ConclusionsDespite the lack of strong evidence found in this systematic review, L‐PRF might have a positive effect on bone regeneration and osseointegration.

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Section: Resultsmentioning

confidence: 99%

Regenerative potential of leucocyte‐ and platelet‐rich fibrin. Part B: sinus floor elevation, alveolar ridge preservation and implant therapy. A systematic review

Castro

Meschi

Temmerman

et al. 2017

J Clinic Periodontology

156

133

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show abstract

“…Only three studies investigated the alterations of the alveolar ridge after postextraction application of platelet derivatives as reported in supplemental table 1 (available at http://content.karger.com/ProdukteDB/produkte.asp?doi=488061 ) [17,18,20]. Four studies investigated the postoperative symptoms and quality of life (e.g.…”

Section: Resultsmentioning

confidence: 99%

“…Soft tissue healing was evaluated in five of the seven studies included [15,16,17,18,19]. A qualitative assessment of hard tissue healing was carried out in five of the seven included studies (supplemental table 1, available at http://content.karger.com/ProdukteDB/produkte.asp?doi=488061 ) [15,16,18,20,21].…”

Section: Resultsmentioning

confidence: 99%

“…Two studies [17,20] did not report the cause of extraction at all. Only in one study [16] the authors considered a threshold in terms of residual bone among the inclusion/exclusion criteria.…”

Section: Discussionmentioning

confidence: 99%

“…Besides purely methodological aspects, also other inconsistencies and limitations were evident after a careful reading of some of these papers (e.g. discrepancies between data reported in the text and those presented in the respective tables or graphics in terms of values and/or significance, see also adjunctive notes in supplemental table 1 (available at http://content.karger.com/ProdukteDB/produkte.asp?doi=488061 ) for more details [17,18,19,20]. …”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

The Role of Autologous Platelet Concentrates in Alveolar Socket Preservation: A Systematic Review

Annunziata

Guida

Nastri

et al. 2018

Transfus Med Hemother

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Prevention of alveolar bone resorption after tooth extraction may be useful for implant rehabilitation of the edentulous site minimizing the future need for bone augmentation procedures. A number of studies have investigated the efficacy of autologous platelet concentrates for the preservation of the alveolar bone volume after tooth extraction. Although encouraging results have been published, the available data are still controversial. The aim of the present systematic review was to assess the effect of platelet concentrates on alveolar socket preservation after tooth extraction. A literature search was carried out up to September 2017 for prospective controlled trials in which a test group using exclusively a platelet concentrate was compared with a control group in which extraction sockets were left to heal spontaneously. Seven controlled clinical trials published between 2010 and 2016 were included. A total of 320 extractions (170 tests and 150 controls) in 190 patients was considered. A great heterogeneity was found in terms of study design, methodological aspects, and outcome evaluation. For this reason, a quantitative analysis followed by meta-analysis was not possible, and only a descriptive analysis on the role of platelet concentrates in alveolar socket preservation was carried out. There is growing evidence that platelet concentrates may be advantageously used in postextraction sites, mainly to improve soft tissue healing and to reduce postoperative symptoms. Data about their potential in preserving the alveolar bone volume are still scarce and controversial, although recently encouraging results have been presented using more reliable and accurate evaluation technologies, such as the computed tomography. Further, well-designed and methodologically standardized investigations are strongly demanded to reach a higher level of evidence on this topic.

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Guided Bone Regeneration with Platelet Rich Fibrin

Miron¹,

Pikos²,

Zhang³

et al. 2017

Platelet Rich Fibrin in Regenerative Dentistry: Biological Background and Clinical Indications

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Influence of Platelet-Rich Fibrin on Alveolar Ridge Preservation

Abstract: This preliminary result demonstrated neither better alveolar ridge preservation nor enhanced bone formation of PRF in the extraction socket. The use of PRF revealed limited effectiveness by accelerated soft-tissue healing on the first 4 weeks.

Cited by 103 publications

References 24 publications

Regenerative potential of leucocyte‐ and platelet‐rich fibrin. Part B: sinus floor elevation, alveolar ridge preservation and implant therapy. A systematic review

Regenerative potential of leucocyte‐ and platelet‐rich fibrin. Part B: sinus floor elevation, alveolar ridge preservation and implant therapy. A systematic review

The Role of Autologous Platelet Concentrates in Alveolar Socket Preservation: A Systematic Review

Guided Bone Regeneration with Platelet Rich Fibrin

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