Influence of Polydioxanone Foil on Growing Septal Cartilage After Surgery in an Animal Model

Abstract

To determine whether late complications after septoplasty in growing septal cartilage in children can be prevented by the use of a resorbable polydioxanone (PDS) foil in combination with the cartilage. Design: Animal study with 45 young rabbits, operated on at the nasal septum. Four typical septoplasty procedures were carried out, including elevation of the mucoperichondrium, cartilage excision, and reimplantation of crushed and noncrushed cartilage; for each of the procedures, resorbable PDS foil was used in half of the animals. Observation time ranged from 2 weeks to 5 months, to observe the healing process until complete outgrowth of the septum and complete resorption of the foil were achieved.

Reconstruction of the Nasal Septum Using Polydioxanone Plate

“…Therefore, the combination of nasal septal cartilage and resorbable polydioxanone plate offers technical advantages during the operation and the benefits of a resorbable implant during the healing process. 10 At the time of writing, we had used this technique in 396 patients. Since its original conception, the technique has been further developed to include polydioxanone plate in combination with auricular conchal cartilage.…”

The modern transplants for the restoration of bone defects in rhinology

“…Большой клинический интерес представляют данные о реакции тканей и течение раневого процесса при им-плантации полимерных материалов [47,48]. Так, с целью пластики костного дефекта при остеомах околоносовых пазух с успехом использовались полифосфазеновые эндо-протезы [49], протакрил [26], для закрытия посттравмати-ческого дефекта верхней стенки верхнечелюстной пазухи -силикон [50] или тефлон [51].…”

Chirurgie des Nasenseptums und der Nasenmuscheln

“…Die typischen Veränderungen (das Einsinken des knor− peligen Nasenrückens, verbunden mit einer retrahierten Colu− mella und breiteren Nasenbasis) sind in der Regel auf eine unzu− reichende Fixierung oder Stabilität des knorpeligen ¹L" an der Spina nasalis anterior bzw. K−Region oder auf eine zu ausge− dehnte inferiore und posteriore Chondrotomie (Swinging door) mit unzureichender Refixierung an der Spina nasalis anterior zu− rückzuführen [46,47] …”