Influence of preoperative factors on the oncologic outcome for upper urinary tract urothelial carcinoma after radical nephroureterectomy

Hurel, S.; Rouprêt, Morgan; Seisen, Thomas; Compérat, Éva; Phé, Véronique; Droupy, S.; Audenet, François; Pignot, G.; Cathelineau, Xavier; Guy, Laurent; Cussenot, Olivier; Ouzzane, A.; Bozzini, G.; Nison, L.; Ruffion, A.; Colin, P.

doi:10.1007/s00345-014-1311-8

Cited by 46 publications

(39 citation statements)

References 22 publications

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“…A risk factor similar to those found in the Balkan nephropathy and Chinese herbs recognized and reported in the literature since 1950 [3]. The discovery of TVES is happy chance in 10 to 16% of cases depending on the series with the waning of abdominal imaging performed for another reason [5]. A pleurisy operating in a context of an impaired general condition us discover renal tumor after scannographic etiologic.…”

Section: Tumors Of Upper Tract (Tves)supporting

confidence: 65%

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2017

JLPRR

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The authors illustrate through an observation of an aggressive and exceptional pleural evolution metastatic of a carcinoma urothelial of the upper urinary tract at the origin of an atypical radiological aspect and rarely described of pseudo-mesothelioma. In our case, the instillation with the BCG Pasteur by the percutaneous nephrostomy and the pleur X with the profit of a heavy chemotherapy enabled us to in fact circumvent the evolution towards the acute complications related to this pathology, the malignant pleuresis.Keywords: BCG; Chemotherapy; Differential diagnosis; Mesothelioma; Radiotherapy; Surgery; Urothelial carcinomaThe authors describe here the first Malagasy case of urothelial carcinoma of the upper urinary tract radiological discovery late in pleural metastatic and discuss differential diagnoses of the image and the evolution of this tumor treated with topical agent adjuvant through review of recent literature. ObservationMr RAV. 53 years old, no smoking was hospitalized for progressive worsening of dyspnea lasting for 6 months, accompanied by chest pain basi-left. In the interview we noted a notion regularly taking a decoction of clinical médicinales. L'examen virtues plants entering found an alteration of the general status (PS = 3 according to WHO), a left pulmonary syndrome without condensation fever. Radiography of thorax face showed pleural thickening picture left scalloped. Chest CT (Figure 1) confirmed the pleural lesions secondary look and abdominopelvic CT scan for staging (Figure 2) found a retroperitoneal mass compatible of renal tumor primitive right. Biologically, there was a LDH assay was raised to 1423 IU/ml (5 times normal). Histological examination of a biopsy transthoracic puncture confirmed the location of a secondary urothelial carcinoma at the pleura (pT4N2M1) (Figure 3). Our patient had received a course of BCG instillation Pasteur by percutaneous nephrostomy and the tear-X (thoracic drainage system) and died after three months of decline following the natural evolution of the tumor.

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Section: Tumors Of Upper Tract (Tves)supporting

confidence: 65%

Untitled

2017

JLPRR

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“…The secondary sign of hydronephrosis is associated with advanced disease and poor oncologic outcome [1,25,26]. The presence of enlarged lymph nodes is highly predictive of metastasis in UTUC [1].…”

Section: Symptomsmentioning

confidence: 99%

European Association of Urology Guidelines on Upper Urinary Tract Urothelial Cell Carcinoma: 2015 Update

et al. 2015

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“…A risk factor similar to those found in the Balkan nephropathy and Chinese herbs recognized and reported in the literature since 1950 (3) . UTUC are discovered incidentally in 10 to 16% of cases due to a series of waning in abdominal imaging performed for another reason (5) . Pleurisy operating in a context of an impaired general condition enabled us to discover renal tumor after scannographic etiologic.…”

Section: Upper Tract Urothelial Carcinoma (Utuc)mentioning

confidence: 99%

A Pseudo-Mesothelioma Pleural Revealing a Carcinoma Urothelial Metastatic: a Case and Review of the Literature

Mihaja¹,

Ravoatrarilandy²,

Herilala³

et al. 2017

IAM

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The authors illustrate through the observation of an aggressive and exceptional pleural evolution metastatic of a carcinoma urothélial of the upper urinary tract at the source of an atypical and rarely described chest ray aspect of pseudo-mesothelioma. In our case, the instillation with the BCG Pasteur by the percutaneous nephrostomy and the pleurX in favor of a heavy chemotherapy have enabled us to circumvent the evolution towards the acute complications related to this pathology, the malignant pleuresis.

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Influence of preoperative factors on the oncologic outcome for upper urinary tract urothelial carcinoma after radical nephroureterectomy

Abstract: Patients with preoperative impaired renal function, locally advanced stage and multifocal tumours before RNU had worse survival outcomes compared to other patients.

Cited by 46 publications

References 22 publications

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European Association of Urology Guidelines on Upper Urinary Tract Urothelial Cell Carcinoma: 2015 Update

A Pseudo-Mesothelioma Pleural Revealing a Carcinoma Urothelial Metastatic: a Case and Review of the Literature

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