Influence of primary tumor location on resectability of synchronous colorectal liver metastases and oncologic outcomes after liver resection

Abstract

positive nodes. Most of the patients(57%) were treated with FOLFOX scheme. The mean of follow-up was 52 months.The total number of MM identified on baseline imaging was 64.At surgical pathology, 52 of 64 lesions resected demonstrated non-viable-tumor. Recurrence occurred in 44% of patients with a mean follow-up of 10 months +/-2.4 months of which 18%(3 patients) relapsed in situ. Conclusion: In our series, the pathological response rate after chemotherapy in MM, arise up to 80%, which brings us to put into question the current treatment paradigm. We believe it is necessary to restate the surgical treatment in MM when it implies extra risk for the patient, opening the door to a new era where observation can be a reasonable alternative.