Influence of Prostatic Calculi on Lower Urinary Tract Symptoms in Middle-aged Men

Kim, Woong Bin; Doo, Seung Whan; Yang, Won Jae; Song, Yun Seob

doi:10.1016/j.urology.2010.12.056

Cited by 39 publications

(55 citation statements)

References 9 publications

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“…In addition, bacterial biofilm was found in the prostatic stones and high frequency of bacterial imprints was found in these stones by electron microscopy scanning [27][28][29] . Results of the study by Kim et al [4] support these findings, since they showed that prostatic stones could be influenced by antimicrobial therapy in patients with chronic bacterial prostatitis. Namely, after 4 weeks of antimicrobial therapy and follow-up, a greater percentage of organisms were continuously eradicated in patients without prostatic calculi compared to patients with prostatic calculi.…”

Section: Discussionmentioning

confidence: 70%

“…Kim et al [4] demonstrated that presence of large prostatic stones (large masses of multiple echoes, much coarser) was significantly associated with moderate LUTS and the likelihood of an IPSS ≥ 8 was related to the large stones group of patients with a 1.784-fold lower risk for IPSS ≥ 8 in patients with no or small prostatic stones. According to the study by Geramoutsos et al [6], patients with symptoms (LUTS and CP/CPPS-related symptoms) have fold higher probability of having large stones compared with asymptomatic patients.…”

Section: Discussionmentioning

confidence: 99%

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Clinical and Biochemical Influence of Prostatic Stones

Sorić

Selimović²,

Bakovic³

et al. 2017

Urol Int

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Introduction: The study aimed to explore clinical influence of prostatic stones on lower urinary tract symptoms (LUTS), seminal plasma cytokines, and serum biomarkers. Materials and Methods: A total of 70 men aged ≤50 years with LUTS divided into 2 groups: group with stones (GSt) and group without prostatic stones (GNoSt). All subjects completed the International Prostate Symptom Score (IPSS) questionnaire and National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) scoring questionnaire. Pre- and post-prostate massage test and uroflowmetry were performed. The serum concentration of total prostate specific antigen (PSA), free PSA, and free/total PSA (f/t PSA) ratio, seminal concentration of cytokines interleukin (IL)-1β, IL-6, IL-8, IL-10, IL-12p70, and tumor necrosis factor-alpha were measured. Results: GSt subjects had significantly more severe symptoms based on IPSS answers (p = 0.0289). All domains in NIH-CPSI scores were significantly higher in the GSt group: pain (p = 0.001), urinary symptoms (p = 0.023), quality of life (p = 0.008), and with overall (p = 0.003). GSt subjects also had significantly lower maximum urinary flow (Qmax; p = 0.011), lower f/t PSA ratio (p = 0.048), and higher concentration of IL-1β (p = 0.011) and IL-8 (p = 0.001). Conclusions: Prostatic stones may influence the severity of LUTS and the symptoms of chronic prostatitis. They might reduce Qmax rate and lead to reduction of the f/t PSA ratio and produce more severe inflammation causing increased seminal concentration of IL-1β and IL-8.

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Section: Discussionmentioning

confidence: 70%

Section: Discussionmentioning

confidence: 99%

Clinical and Biochemical Influence of Prostatic Stones

Sorić

Selimović²,

Bakovic³

et al. 2017

Urol Int

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“…In a postmortem study made with microradiographic examination, while prostatic calcifications were reported in 71% of the patients, this ratio was found to be 25.3% in prostate biopsies [2,9]. The prevalence of PCal observed in TRUS made due to different urological complaints was found to be between 40.7 and 86% and it was shown that its prevalence increased with age [6,10]. With a significant decrease in PCal detection ratios based on TRUS in transabdominal imagings, the ratio was detected as 7.35% [9].…”

Section: Discussionmentioning

confidence: 93%

“…Although PCal prevalence was observed to be interestingly high for the urologists in daily urology practice, the prevalence data are not certain in the general population [6]. To date, there are no systematic survey studies using appropriate methods, and a standard definition of PCal has not been established.…”

Section: Discussionmentioning

confidence: 99%

“…To date, there are no systematic survey studies using appropriate methods, and a standard definition of PCal has not been established. PCal are asymptomatic in clinical terms and considered to be related to lower urinary system symptoms generally [6,7]. PCal are randomly observed during X-ray graphics, pelvic/transrectalultrasonograpy, and CT scanning studies made for the diagnosing urological complaints and generally during the transurethral resection of prostate [8].…”

Section: Discussionmentioning

confidence: 99%

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Is There A Relation Between Serum Uric Acid Values and Prostatic Calculi Presence?

Balasar¹,

Sönmez²,

Aydın³

et al. 2018

Urol Int

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Objective: We planned to examine the connection between serum uric acid (UA) values and prostatic calculi (PCal) presence and to evaluate the relation between PCal and other etiological factors. Methods: Patients between 20 and 60 years of age who were referred to the clinic with any reason and had non-contrast abdominal tomography (NCACT) for PCal were included in the study. While the patients were separated into 2 groups based on their serum UA level as ≥7 mg/dL (Group 1) and < 7 mg/dL (Group 2), NCACT was also divided into 2 groups as PCal presence (PCal+) and lack (PCal–) serum UA, calcium, phosphorus, sodium, prostate-specific antigen levels and urinary analysis results of the patients were evaluated and compared. Results: PCal were detected in 38 of 169 patients (22%). PCal presence was detected to be significantly high in Group 1 (p = 0.015). While Type A localization PCal were present both in Groups 1 and 2. Based on PCal presence, UA level was detected to be significantly high in PCal+ patients (p = 0.01). No significant difference was detected among the groups in biochemical parameters and urine-related parameters other than UA. Conclusion: A significant relation was found between high UA value and PCal in this study. These results may show that UA plays an active role in PCal etiology.

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Susceptibility‐weighted imaging: current status and future directions

Liu¹,

Buch²,

et al. 2016

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Susceptibility weighted imaging (SWI) is a method that uses the intrinsic nature of local magnetic fields to enhance image contrast in order to improve the visibility of various susceptibility sources and to facilitate the diagnostic interpretation. It is also the precursor to the concept of using phase for quantitative susceptibility mapping (QSM). Nowadays, SWI has become a widely used clinical tool to image deoxyhemoglobin in veins, iron deposition in the brain, hemorrhages, microbleeds, and calcification. In this paper, we review the basics of SWI, including data acquisition, data reconstruction and post-processing. In particular, the source of cusp artifacts in phase images is investigated in detail and an improved multi-channel phase data combination algorithm is provided. In addition, we show a few clinical applications of SWI for imaging stroke, traumatic brain injury, carotid vessel wall, siderotic nodules in cirrhotic liver, prostate cancer, prostatic calcification, spinal cord injury and intervertebral disc degeneration. As the clinical applications of SWI continue to expand both in and outside the brain, improving SWI in conjunction with QSM is an important future direction of this technology.

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Influence of Prostatic Calculi on Lower Urinary Tract Symptoms in Middle-aged Men

Cited by 39 publications

References 9 publications

Clinical and Biochemical Influence of Prostatic Stones

Clinical and Biochemical Influence of Prostatic Stones

Is There A Relation Between Serum Uric Acid Values and Prostatic Calculi Presence?

Susceptibility‐weighted imaging: current status and future directions

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