Influence of Repeated Ischaemia/Reperfusion Cycles (Ischaemic Preconditioning) on Human Calf Energy Metabolism by Simultaneous Near Infrared Spectroscopy, 31P-NMR and 23Na-NMR Measurements

Binzoni, Tiziano; Quaresima, Valentina; Hiltbrand, E.; Gürke, Lorenz; Cerretelli, Paolo; Ferrari, Marco

doi:10.1007/978-1-4615-5399-1_75

Cited by 6 publications

(6 citation statements)

References 8 publications

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“…Moreover, arterial occlusion (AO) was applied in 15 studies (4,(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36). Two studies included data on ischemia in the absence of exercise (29,30). All other studies involve training and/or post-exercise recovery.…”

Section: Study Characteristicsmentioning

confidence: 99%

A Systematic Review of the Relationship Between Muscle Oxygen Dynamics and Energy Rich Phosphates. Can NIRS help?

Maliszewski

Feldmann

McCully³

et al. 2023

Preprint

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Background: Phosphocreatine dynamics provide the gold standard evaluation of in-vivo mitochondrial function and is tightly coupled with oxygen availability. Low mitochondrial oxidative capacity has been associated with health issues and low exercise performance. Methods: To evaluate the relationship between near-infrared spectroscopy-based muscle oxygen dynamics and magnetic resonance spectroscopy-based energy-rich phosphates, a systematic review of the literature related to muscle oxygen dynamics and energy-rich phosphates was conducted. PRISMA guidelines were followed to perform a comprehensive and systematic search of four databases on 02-11-2021 (PubMed, MEDLINE, Scopus and Web of Science). Beforehand pre-registration with the Open Science Framework was performed. Studies had to include healthy humans aged 18-55, measures related to NIRS-based muscle oxygen measures in combination with energy-rich phosphates. Exclusion criteria were clinical populations, laboratory animals, acutely injured subjects, data that only assessed oxygen dynamics or energy-rich phosphates, or grey literature. The Effective Public Health Practice Project Quality Assessment Tool was used to assess methodological quality, and data extraction was presented in a table. Results: Out of 1483 records, 28 were eligible. All included studies were rated moderate. The studies suggest muscle oxygen dynamics could indicate energy-rich phosphates under appropriate protocol settings. Conclusion: Arterial occlusion and exercise intensity might be important factors to control if NIRS application should be used to examine energetics. However, more research needs to be conducted without arterial occlusion and with high-intensity exercises to support the applicability of NIRS and provide an agreement level in the concurrent course of muscle oxygen kinetics and muscle energetics. Trial Registration: https://osf.io/py32n/

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Section: Study Characteristicsmentioning

confidence: 99%

A Systematic Review of the Relationship Between Muscle Oxygen Dynamics and Energy Rich Phosphates. Can NIRS help?

Maliszewski

Feldmann

McCully³

et al. 2023

Preprint

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“…NIRS has also been very actively applied to the study of I/R injury in the kidney (Vaughan et al 1995a, Vaughan et al 1995b), liver (El-Desoky et al 2001, El-Desoky et al 1999), skin (Thorniley et al 1998) and muscle (Binzoni et al 1997, Gentilello et al 2001) as well as to the study of compartment syndrome (Giannotti et al 2000, Tobias and Hoernschemeyer 2007). …”

Section: Introductionmentioning

confidence: 99%

“…Near-infrared spectroscopy (NIRS) has been applied to study various sites within the body including the brain (Schecklmann et al 2008), muscle (Wolf et al 2007) and breast (Tromberg et al 2000, Cerussi et al 2007 by providing information on oxy-, deoxy-, total hemoglobin and tissue oxygen saturation non-invasively. NIRS has also been very actively applied to the study of I/R injury in the kidney (Vaughan et al 1995a, Vaughan et al 1995b, liver (El-Desoky et al 2001, El-Desoky et al 1999, skin (Thorniley et al 1998) and muscle (Binzoni et al 1997, Gentilello et al 2001 as well as to the study of compartment syndrome (Giannotti et al 2000, Tobias andHoernschemeyer 2007).…”

Section: Introductionmentioning

confidence: 99%

Hemodynamic changes in rat leg muscles during tourniquet-induced ischemia-reperfusion injury observed by near-infrared spectroscopy

Kim¹,

Lee²,

Roe³

et al. 2009

Physiol. Meas.

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In this study, we hypothesized that non-invasive continuous wave near-infrared spectroscopy (CWNIRS) can determine the severity or reversibility of muscle damage due to ischemia/reperfusion (I/R), and the results will be highly correlated with those from physical examination and histological analysis. To test this hypothesis, we performed CWNIRS measurements on two groups of male Sprague-Dawley rats (~400 g) that underwent 2 h (n = 6) or 3 h (n = 7) of pneumatic tourniquet application (TKA). Tissue oxyhemoglobin [HbO2] and deoxyhemoglobin [Hb] concentration changes were monitored during the 2 h or 3 h of 250 mmHg TKA and for an additional 2 h post-TKA. Rats were euthanized 24 h post-TKA and examined for injury, edema and viability of muscles. Contralateral muscles served as controls for each animal. In both groups, [HbO2] dropped immediately, then gradually decreased further after TKA and then recovered once the tourniquet was released. However, releasing after 2 h of TKA caused [HbO2] to overshoot above the baseline during reperfusion while the 3 h group continued to have lower [HbO2] than baseline. We found a significant correlation between the elapsed time from tourniquet release to the first recovery peak of [HbO2] and the muscle weight ratio between tourniquet and contralateral limb muscles (R = 0.86). Hemodynamic patterns from non-invasive CWNIRS demonstrated significant differences between 2 h and 3 h I/R. The results demonstrate that CWNIRS may be useful as a non-invasive prognostic tool for conditions involving vascular compromise such as extremity compartment syndrome.

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“…NIRS has also been very actively applied to the study of I/R injury in the kidney (Vaughan et al 1995a, Vaughan et al 1995b, liver (El-Desoky et al 2001, El-Desoky et al 1999, skin (Thorniley et al 1998) and muscle (Binzoni et al 1997, Gentilello et al 2001 as well as to the study of compartment syndrome (Giannotti et al 2000, Tobias andHoernschemeyer 2007).…”

mentioning

confidence: 99%

Hemodynamic Changes in Rat Leg Muscles During Tourniquet-Induced Ischemia-Reperfusion Injury Observed by Near Infrared Spectroscopy

Kim

Lee

Walters

et al. 2007

Chest

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In this study, we hypothesized that non-invasive continuous wave near-infrared spectroscopy (CWNIRS) can determine the severity or reversibility of muscle damage due to ischemia/reperfusion (I/R), and the results will be highly correlated with those from physical examination and histological analysis. To test this hypothesis, we performed CWNIRS measurements on two groups of male Sprague-Dawley rats (~400 g) that underwent 2 h (n = 6) or 3 h (n = 7) of pneumatic tourniquet application (TKA). Tissue oxyhemoglobin [HbO 2 ] and deoxyhemoglobin [Hb] concentration changes were monitored during the 2 h or 3 h of 250 mmHg TKA and for an additional 2 h post-TKA. Rats were euthanized 24 h post-TKA and examined for injury, edema and viability of muscles. Contralateral muscles served as controls for each animal. In both groups, [HbO 2 ] dropped immediately, then gradually decreased further after TKA and then recovered once the tourniquet was released. However, releasing after 2 h of TKA caused [HbO 2 ] to overshoot above the baseline during reperfusion while the 3 h group continued to have lower [HbO 2 ] than baseline. We found a significant correlation between the elapsed time from tourniquet release to the first recovery peak of [HbO 2 ] and the muscle weight ratio between tourniquet and contralateral limb muscles (R = 0.86). Hemodynamic patterns from non-invasive CWNIRS demonstrated significant differences between 2 h and 3 h I/R. The results demonstrate that CWNIRS may be useful as a non-invasive prognostic tool for conditions involving vascular compromise such as extremity compartment syndrome.

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Influence of Repeated Ischaemia/Reperfusion Cycles (Ischaemic Preconditioning) on Human Calf Energy Metabolism by Simultaneous Near Infrared Spectroscopy, 31P-NMR and 23Na-NMR Measurements

Cited by 6 publications

References 8 publications

A Systematic Review of the Relationship Between Muscle Oxygen Dynamics and Energy Rich Phosphates. Can NIRS help?

A Systematic Review of the Relationship Between Muscle Oxygen Dynamics and Energy Rich Phosphates. Can NIRS help?

Hemodynamic changes in rat leg muscles during tourniquet-induced ischemia-reperfusion injury observed by near-infrared spectroscopy

Hemodynamic Changes in Rat Leg Muscles During Tourniquet-Induced Ischemia-Reperfusion Injury Observed by Near Infrared Spectroscopy

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