Influence of Reproductive Season upon Plasma Biochemistry Values in Green Iguanas

Knotková, Z.; Pejřilová, S.; Trnková, Šárka; Matousková, O; Knotek, Z.

doi:10.2754/avb200574040515

Cited by 16 publications

(18 citation statements)

References 12 publications

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“…All haematological and biochemical parameters remained within the physiological range of healthy individuals (Harr et al, 2001;Knotek et al, 2002;Pejrilova et al, 2004;Knotkova et al, 2005). The lower concentration of haemoglobin, PCV and RBC could be explained by haemodynamic changes and re-distribution of blood cellular elements in the vascular bed.…”

Section: Discussionmentioning

confidence: 81%

“…When evaluating anaesthetics in reptiles it is good to check blood parameters which characterize the inner environment and its state in the species being studied. There is sufficient data on haematological and biochemical profiles both in healthy green iguanas and clinical patients Bruder, 1998;Harr et al, 2001;Knotek et al, 2002;Pejrilova, et al, 2004;Knotkova et al, 2005). The aim of this study was to evaluate selected blood parameters during short-term anaesthesia with propofol in the green iguana (Iguana iguana rhinolopha).…”

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confidence: 99%

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Blood profile in green iguanas after short-term anaesthesia with propofol

Knotková¹,

Knotek²,

Trnková³

et al. 2006

Vet. Med. - Czech

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Blood haematology and plasma chemistry profiles were examined in a group of ten 17 months-old green iguanas two minutes before propofol administration (10 mg/kg of body weight) and two minutes after recovery from anaesthesia. The induction time was very short (35.50 ± 22.54 s), the recovery time was 21.50 ± 7.44 minutes. At five and fifteen minutes of anaesthesia there was a considerable drop in the heart rate. The most marked drop, however, was noted during the tenth minute. Following the administration of propofol green iguanas showed marked changes in the respiratory frequency that were not accompanied by any changes in the levels of SpO2. RBC (1.06 ± 0.08 vs. 1.21 ± 0.06 1012/l) were decreased with a high significance (P < 0.01) two minutes after recovery from the propofol anaesthesia. At the same time there was a significant (P < 0.05) decrease of haemoglobin concentration (76.70 ± 13.39 vs. 83.73 ± 9.24 g/l) and PCV (0.34 ± 0.04 vs. 0.36 ± 0.04 l/l) as well as a significant (P < 0.05) increase of WBC (7.95 ± 3.38 vs. 5.20 ± 2.52 109/l), heterophils (3.14 ± 1.48 vs. 1.43 ± 0.43 109/l) and basophils (0.60 ± 0.53 vs. 0.23 ± 0.17 109/l). The following parameters increased two minutes after anaesthesia with a high significance (P < 0.01): plasma concentration of total protein (55.12 ± 5.94 vs. 49.02 ± 3.54 g/l), uric acid (231.07 ± 77.69 vs. 157.58 ± 60.58 µmol/l), AST (1.23 ± 0.52 vs. 0.67 ± 0.34 µkat/l), TAG (3.37 ± 1.11 vs. 1.48 ± 0.78 mmol/l), phosphorus (2.29 ± 0.38 vs. 1.85 ± 0.35 mmol/l). The increase in plasma calcium levels (3.51 ± 0.11 vs. 3.21 ± 0.23 mmol/l) was significant at the level of P < 0.05. All the measured values were within the reference range of healthy green iguanas.

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Section: Discussionmentioning

confidence: 81%

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confidence: 99%

Blood profile in green iguanas after short-term anaesthesia with propofol

Knotková¹,

Knotek²,

Trnková³

et al. 2006

Vet. Med. - Czech

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“…Repeated doses of carprofen induced higher levels of AST (0.82 ± 0.26 μkat/l) than saline (P < 0.01, 0.31 ± 0.16 μkat/l) or meloxicam (P < 0.05, 0.38 ± 0.16 μkat/l). Blood parameters of both experimental groups of iguanas were within physiological reference values of healthy green iguanas (Pejrilova et al, 2004;Knotkova et al, 2005Knotkova et al, , 2006. The mean values of haematological and biochemical parameters of experimental green iguanas are shown in tables (Table 1 and 2).…”

Section: Resultsmentioning

confidence: 97%

Effect of non-steroidal anti-inflammatory drugs on the blood profile in the green iguana (Iguana iguana)

Trnková¹,

Knotková²,

Hrdá³

et al. 2007

Vet. Med. - Czech

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A total of 20 healthy green iguanas (14 males and six females with body weight ranging from 280 to 720 g) were divided into three groups and used for the experiment. Carprofen (2.0 mg/kg, i.m.) was administered to seven iguanas for 10 days, five were treated with meloxicam (0.2 mg/kg, i.m.) for the same period, and eight iguanas received the same volume of saline solution (0.04 ml/kg). All iguanas were blood sampled on Day 1 and 11 to obtain haematological and biochemical parameters. Comparing the values within particular groups, a decrease in haemoglobin concentration and packed cell volume accompanied by an increase in azurophils (P < 0.05) was observed in iguanas treated with carprofen. Decreased values of haemoglobin and packed cell volume were also found in control iguanas (P < 0.05). Increased ALT levels (P < 0.01) were found in all three groups of iguanas. A decrease in the concentration of Ca (P < 0.01) was observed both in meloxicam-treated iguanas and in the control ones. Mean ALT values of carprofen-treated iguanas (2.42 ± 0.52 μkat/l) were considerably higher (P < 0.01) than those in iguanas treated with meloxicam (0.49 ± 0.18 μkat/l) or saline (0.43 ± 0.13 μkat/l). Repeated doses of carprofen induced higher levels of AST (0.82 ± 0.26 μkat/l) compared with saline (P < 0.01, 0.31 ± 0.16 μkat/l) or meloxicam (P < 0.05, 0.38 ± 0.16 μkat/l). All blood parameters of green iguanas following the 10-day intramuscular administration of both carprofen and meloxicam were within the physiological reference values of this species.within the physiological reference values of this species.

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“…Plasma biochemical assays were performed within 2 h after collection by the use of automated analyzers (Knotková et al 2005). The activity of ALP, ALT, AST and creatinephosphokinase (CPK), as well as concentration of total protein, glucose, uric acid, cholesterol, triglycerides (TAG) and phosphorus was determined with a CobasMira analyzer (Roche, Switzerland); plasma concentrations of calcium were determined using a AA Series Spectrometer (Thermo Electron Corporation, UK).…”

Section: Methodsmentioning

confidence: 99%

Hepatocellular carcinoma in a green iguana – a case study

et al. 2011

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A 3.10 kg, six-year old male green iguana (Iguana iguana) suffered several weeks of decreased activity, loss of body weight, anorexia and change of skin colour. Physical examination revealed a cachectic depressed lizard, with marked pale mucous membranes. The complete blood count revealed a leukocytosis (46.5 × 10 9 /l), elevated heterophils (23.25 × 10 9 /l) and azurophils (23.25 × 10 9 /l), decreased haemoglobin concentration (29.00 g/l), low haematocrit (0.16 l/l) and erythropenia (0.35 × 10 12 /l). Abnormalities of the plasma chemistry panel included increased activity of aspartate aminotransferase (6.05 μkat/l) and creatinephosphokinase (217.91 μkat/l), increased concentrations of uric acid (321.58 μmol/l), phosphorus (4.04 mmol/l) and bile acids (120.21 μmol/l), as well as a decreased concentration of glucose (3.72 mmol/l), cholesterol (0.637 mmol/l) and triglycerides (0.09 mmol/l). A lateral radiograph revealed soft-tissue opacity present in the region of the liver. Magnetic resonance imaging showed a markedly enlarged left liver lobe distended caudally and displacing the other abdominal organs. The signal intensity of the liver parenchyma was slightly hyperintense, the ventro-medial part of the left lobe showed a hypointense signal. Endoscopic examination of the coelomic cavity revealed a greatly enlarged pale liver and the presence of a straw-coloured modified transudate. Based on histopathological examination of the liver hepatocellular carcinoma was diagnosed. Despite supportive treatment the patient died on the sixth day of hospitalisation. Reptiles, liver disease, plasma chemistry, bile acids, MRIDifferent types of liver diseases are common in captive reptiles. Monitoring of liver function in reptiles is not easy and cannot be based purely on measuring the activities of plasma enzymes like alkaline phosphatase (ALP), alanine aminotransferase (ALT), and aspartate aminotransferase (AST), because the large reserve capacity of the reptilian liver function makes such evaluation incorrect. Using magnetic resonance imaging (MRI) to assess focal lesions of the spleen and liver has been well documented in dogs (Clifford et al. 2004) and the diffuse and focal pathological processes in different organs and soft tissues are documented with MRI imagines in human and veterinary medicine (Gumpenberger and Henniger 2001;Oliva and Saini 2004;Bialecki and Bisceglie 2005;Aguirre et al. 2006;Hecht et al. 2006;Silverman 2006;Elsayes et al. 2007;Knotek et al. 2007;Szklaruk and Bhosale 2007). Materials and MethodsA 3.10 kg, six-year old male green iguana (Iguana iguana) suffered several weeks of decreased activity, continuing loss of body weight, anorexia and change of skin colour. The iguana was kept as a single pet indoors in a terrarium (1.45 × 0.9 × 0.6 m) with temperature ranges between 24 and 35 °C, air humidity between 60 and 80% and a specific light regime (12h/12 h of light and dark, 100 W bulb + UV lamp Repti-Glo 5.0, Hagen). The diet

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Influence of Reproductive Season upon Plasma Biochemistry Values in Green Iguanas

Cited by 16 publications

References 12 publications

Blood profile in green iguanas after short-term anaesthesia with propofol

Blood profile in green iguanas after short-term anaesthesia with propofol

Effect of non-steroidal anti-inflammatory drugs on the blood profile in the green iguana (Iguana iguana)

Hepatocellular carcinoma in a green iguana – a case study

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