Influence of Saturated Fat and Linolenic Acid on the Association Between Intake of Dairy Products and Blood Pressure

Djoussé, Luc; Pankow, James S.; Hunt, Steven C.; Heiss, Gerardo; Province, Michael A.; Kabagambe, Edmond K.; Ellison, R. Curtis

doi:10.1161/01.hyp.0000229668.73501.e8

Cited by 37 publications

(32 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The association between dairy product intake and BP, hypertension have been examined more in cross-sectional studies [21][22][23][24] than in prospective studies. 8 -10 The Framingham Children's Study found that children who consumed 2 or more servings/d dairy products during preschool years had smaller SBP gain throughout childhood and lower SBP by early adolescence.…”

Section: Discussionmentioning

confidence: 99%

Dietary Intake of Dairy Products, Calcium, and Vitamin D and the Risk of Hypertension in Middle-Aged and Older Women

et al. 2008

View full text Add to dashboard Cite

Abstract-Prospective data on the associations between intake of dairy products and its nutrient components with risk of hypertension remain limited. We therefore investigated the associations of intake of dairy products, calcium, and vitamin D with the incidence of hypertension in a prospective cohort of 28 886 US women aged Ն45 years. Intake of dairy products, calcium, and vitamin D at baseline were assessed from semiquantitative food frequency questionnaires. Incident cases of hypertension (nϭ8710) were identified from annual follow-up questionnaires during 10 years of follow-up. After adjusting for major hypertension risk factors, the relative risks of incident hypertension across increasing quintiles of low-fat dairy product intake were 1.00 (reference), 0. Key Words: diet Ⅲ dairy products Ⅲ calcium Ⅲ vitamin D Ⅲ hypertension Ⅲ women Ⅲ population study P revious studies have suggested an inverse association of dairy product consumption with metabolic syndrome, 1 type 2 diabetes, 2 and cardiovascular disease. 3 These potential benefits of dairy consumption are usually attributed to major nutrients in dairy products such as calcium. High calcium intake decrease levels of parathyroid hormone and 1,25-(OH) 2 vitamin D and thus reduce calcium influx from outside the cell. 4 Reduced intracellular calcium may stimulate lipolysis and inhibit lipogenesis, 5 promote insulin-stimulated signal transduction, 4 and suppress vascular smooth muscle tone. 6 Because vitamin D is critical for calcium absorption and homeostasis, 7 the metabolism of these 2 nutrients are intimately interrelated.Population studies on the associations between dairy product consumption and the incidence of hypertension or increase in blood pressure (BP) have been limited to children, 8 young adults, 1,9 and adults in Mediterranean countries, 10 with results generally suggesting an inverse association. The Dietary Approaches to Stop Hypertension (DASH) trial has demonstrated that a combined diet rich in fruits, vegetables, and low-fat dairy products and low in total and saturated fat effectively reduced BP in subjects with and without hypertension, and the BP lowering effects of the combined diet with emphasis on dairy consumption were more profound compared with a diet rich in fruits and vegetables alone. 11 To provide further evidence on the potential role of dairy consumption in prevention of hypertension, we examined the prospective associations between intake of dairy products, from both high-fat and low-fat food sources, as well as the major nutrient components in dairy products, calcium and vitamin D, with the risk of hypertension in a large cohort of middle-aged and older US women. Methods Study PopulationThe Women's Health Study (WHS) was a randomized, double-blind, placebo-controlled, 2ϫ2 factorial trial evaluating the risks and benefits of low-dose aspirin and vitamin E in the primary prevention of cardiovascular disease and cancer. 12 A third component, ␤-carotene, was initially included in the trial but terminated after a median treatme...

show abstract

Section: Discussionmentioning

confidence: 99%

Dietary Intake of Dairy Products, Calcium, and Vitamin D and the Risk of Hypertension in Middle-Aged and Older Women

et al. 2008

View full text Add to dashboard Cite

show abstract

“…(51) , women; ( ), Abbott et al (57) ; ( ), Engberink et al (59) ; ( ), Djousse et al (212) ; ( ), Liu et al (55) ; ( ), Umesawa et al (63) men; ( ), Umesawa et al (63) women; ( ), Alonso et al (58) ; ( ), Wang et al (213) ; ( ), Mirmiran et al (24) men; ( ), Mirmiran et al (24) women; ( ), Murakami et al (26) ; ( ), Snijder et al (29) ; ( ), Liu et al…”

Section: Evidence From Intervention Trials Without Energy Restrictionmentioning

confidence: 99%

Associations between dairy consumption and body weight: a review of the evidence and underlying mechanisms

et al. 2011

View full text Add to dashboard Cite

As the incidence of obesity is reaching 'epidemic' proportions, there is currently widespread interest in the impact of dietary components on body-weight and food intake regulation. The majority of data available from both epidemiological and intervention studies provide evidence of a negative but modest association between milk and dairy product consumption and BMI and other measures of adiposity, with indications that higher intakes result in increased weight loss and lean tissue maintenance during energy restriction. The purported physiological and molecular mechanisms underlying the impact of dairy constituents on adiposity are incompletely understood but may include effects on lipolysis, lipogeneis and fatty acid absorption. Furthermore, accumulating evidence indicates an impact of dairy constituents, in particular whey protein derivatives, on appetite regulation and food intake. The present review summarises available data and provides an insight into the likely contribution of dairy foods to strategies aimed at appetite regulation, weight loss or the prevention of weight gain.

show abstract

“…Também nesse estudo o efeito foi maior entre os que consumiam menos gorduras saturadas. Os autores também não encontraram evidência de interação entre ácido linolênico e consumo de derivados de leite na HA (Djousse, et al, 2006).…”

Section: Derivados Do Leiteunclassified

Epidemiologia nutricional

Kac¹,

Sichieri²,

Gigante³

2007

View full text Add to dashboard Cite

show abstract

Influence of Saturated Fat and Linolenic Acid on the Association Between Intake of Dairy Products and Blood Pressure

Cited by 37 publications

References 32 publications

Dietary Intake of Dairy Products, Calcium, and Vitamin D and the Risk of Hypertension in Middle-Aged and Older Women

Dietary Intake of Dairy Products, Calcium, and Vitamin D and the Risk of Hypertension in Middle-Aged and Older Women

Associations between dairy consumption and body weight: a review of the evidence and underlying mechanisms

Epidemiologia nutricional

Contact Info

Product

Resources

About