Influence of segmental spinal cord perfusion on intrathecal oxygen tension during experimental thoracic aortic crossclamping

Abstract

In this experimental model of aortic crossclamping, continuous CSF oxygen tension monitoring allows rapid detection of alterations in spinal cord circulation.

Monitoring of intrathecal oxygen tension during experimental aortic occlusion predicts ultrastructural changes in the spinal cord

“…This method was validated with epidural laser Doppler flowmetry. 1,2 The percutaneous use of the Paratrend catheter was also reported in a patient undergoing thoracoabdominal aortic surgery. 3 Recently, Ishizaki and coworkers 16 have reported the use of a rigid mass spectrometer probe for CSF PO 2 measurements during experimental aortic occlusion for identification of spinal cord feeding arteries.…”

“…The present study was designed to evaluate the correlation between CSF parameters derived with the Paratrend catheter and structural changes in the spinal cord in a previously reported aortic occlusion model in pigs. 1 Other studies on spinal cord ischemia have demonstrated a satisfactory correlation between histopathologic spinal cord changes and functional outcome evaluated by use of the Tarlov criteria. [17][18][19][20][21][22] Yamamoto and coworkers 21 observed no morphologic ischemic spinal cord degeneration if normal hind leg function was present.…”