Influence of Short Central PEO Segment on Hydrolytic and Enzymatic Degradation of Triblock PCL Copolymers

Ponjavić, Marijana; Nikolić, Marija S.; Jeremić, Sanja; Djokić, Lidija; Nikodinovic-Runic, Jasmina; Ćosović, Vladan; Djonlagić, Jasna

doi:10.1007/s10924-017-1130-2

Cited by 9 publications

(5 citation statements)

References 44 publications

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“…Upon 4-week exposure to total protein extracts from tested strains, both materials showed surface erosion with a moderate weight loss of 1 -1.3% when P. chlororaphis B-561 was utilized on both materials (Table 1). Ponjavic et al used cell free extracts, containing intracellular fraction of the proteins, from the opportunistic pathogen Pseudomonas aeruginosa PAO1 and obtained similar weight loss of high molecular weight PCL polymer (Ponjavic et al, 2017b, Ponjavic et al, 2017a. Hermanova and co-workers reported degradation of PCL in phosphate buffer by commercial lipase from fungus Aspergillus orizae, with 3.3% of weight loss after 4 weeks of incubation (Hermanova et al, 2012), which is around 2.2 times higher than the weight loss achieved with total proteins from P. chlororaphis B-561.…”

Section: Accepted Manuscriptmentioning

confidence: 95%

Biodegradation of poly(ε-caprolactone) (PCL) and medium chain length polyhydroxyalkanoate (mcl-PHA) using whole cells and cell free protein preparations of Pseudomonas and Streptomyces strains grown on waste cooking oil

Mandic¹,

Spasic²,

Ponjavić

et al. 2019

Polymer Degradation and Stability

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Section: Accepted Manuscriptmentioning

confidence: 95%

Biodegradation of poly(ε-caprolactone) (PCL) and medium chain length polyhydroxyalkanoate (mcl-PHA) using whole cells and cell free protein preparations of Pseudomonas and Streptomyces strains grown on waste cooking oil

Mandic¹,

Spasic²,

Ponjavić

et al. 2019

Polymer Degradation and Stability

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“…In a demonstration of the prototype, a bioresorbable pressure sensor, using the same core materials and structures as described in the previous literature 36 , has been successfully encapsulated with 20% C SS polymers (Fig. 8A).…”

Section: Device Prototypingmentioning

confidence: 99%

Resorbable barrier polymers for flexible bioelectronics

McDonald,

Yang,

Hsu

et al. 2023

Nat Commun

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Resorbable, implantable bioelectronic devices are emerging as powerful tools to reliably monitor critical physiological parameters in real time over extended periods. While degradable magnesium-based electronics have pioneered this effort, relatively short functional lifetimes have slowed clinical translation. Barrier films that are both flexible and resorbable over predictable timelines would enable tunability in device lifetime and expand the viability of these devices. Herein, we present a library of stereocontrolled succinate-based copolyesters which leverage copolymer composition and processing method to afford tunability over thermomechanical, crystalline, and barrier properties. One copolymer composition within this library has extended the functional lifetime of transient bioelectronic prototypes over existing systems by several weeks–representing a considerable step towards translational devices.

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“…Enzymatic hydrolysis of PLA samples was performed following standard protocols (Ponjavic et al 2017b(Ponjavic et al , 2018) by using enzyme mix of alcalase 2.4 L FG (Novozymes, batch PLN05554), savinase (Novozymes, GHSFS-1-02-1) and 3 lipases (Serowar PL; Sigma, cat.no. 54327 and Sigma, cat.…”

Section: Enzymatic Biodegradationmentioning

confidence: 99%

Study of PLA pre-treatment, enzymatic and model-compost degradation, and valorization of degradation products to bacterial nanocellulose

Sourkouni

Jeremić

Kalogirou

et al. 2023

World J Microbiol Biotechnol

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It is well acknowledged that microplastics are a major environmental problem and that the use of plastics, both petro- and bio- based, should be reduced. Nevertheless, it is also a necessity to reduce the amount of the already spread plastics. These cannot be easily degraded in the nature and accumulate in the food supply chain with major danger for animals and human life. It has been shown in the literature that advanced oxidation processes (AOPs) modify the surface of polylactic acid (PLA) materials in a way that bacteria more efficiently dock on their surface and eventually degrade them. In the present work we investigated the influence of different AOPs (ultrasounds, ultraviolet irradiation, and their combination) on the biodegradability of PLA films treated for different times between 1 and 6 h. The pre-treated samples have been degraded using a home model compost as well as a cocktail of commercial enzymes at mesophilic temperatures (37 °C and 42 °C, respectively). Degradation degree has been measured and degradation products have been identified. Excellent degradation of PLA films has been achieved with enzyme cocktail containing commercial alkaline proteases and lipases of up to 90% weight loss. For the first time, we also report valorization of PLA into bacterial nanocellulose after enzymatic hydrolysis of the samples.

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Influence of Short Central PEO Segment on Hydrolytic and Enzymatic Degradation of Triblock PCL Copolymers

Cited by 9 publications

References 44 publications

Biodegradation of poly(ε-caprolactone) (PCL) and medium chain length polyhydroxyalkanoate (mcl-PHA) using whole cells and cell free protein preparations of Pseudomonas and Streptomyces strains grown on waste cooking oil

Biodegradation of poly(ε-caprolactone) (PCL) and medium chain length polyhydroxyalkanoate (mcl-PHA) using whole cells and cell free protein preparations of Pseudomonas and Streptomyces strains grown on waste cooking oil

Resorbable barrier polymers for flexible bioelectronics

Study of PLA pre-treatment, enzymatic and model-compost degradation, and valorization of degradation products to bacterial nanocellulose

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