Influence of solvent effects on retention in reversed-phase liquid chromatography and solid-phase extraction using a cyanopropylsiloxane-bonded, silica-based sorbent

Seibert, Donna S.; Poole, Colin F.

doi:10.1007/bf02274195

Cited by 18 publications

(28 citation statements)

References 31 publications

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“…These are characteristic features, similar to those observed for chemically-bonded phases in reversed-phase liquid chromatography when acetonitrile is used as a mobile phase modifier. 22,24,26 These changes seem largely unrelated to the characteristic properties of acetonitrile itself, which is significantly less cohesive, slightly less dipolar and polarizable than water and a much weaker hydrogen-bond acid with similar hydrogen-bond basicity. 27,28 The change in system constants might simply be explained by a dilution of the properties of water by acetonitrile rather than selective absorption of acetonitrile by the mixed micelles, as observed by others.…”

Section: Resultsmentioning

confidence: 99%

Influence of Composition on the Selectivity of a Mixed-micellar Buffer in Micellar Electrokinetic Chromatography

Poole¹,

Poole²

1997

Anal. Commun.

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Section: Resultsmentioning

confidence: 99%

Influence of Composition on the Selectivity of a Mixed-micellar Buffer in Micellar Electrokinetic Chromatography

Poole¹,

Poole²

1997

Anal. Commun.

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“…The same sorbents as those used in reversed-phase LC are utilized. The analogy which exists between the SPE processes and classical elution chromatography has been shown to allow prediction and optimization of the main SPE parameters from data generated by LC [2][3][4][5][6][7]. Among the various tools for selecting the sorbent and predicting the recovery according to the percolated sample volume, the most important is the retention factor of the analyte in water, k w .…”

Section: Selection Of the Extraction Sorbent For Multiresidue Extractionmentioning

confidence: 99%

Multiresidue solid-phase extraction for trace-analysis of pesticides and their metabolites in environmental water

Pichon¹

1998

Analusis

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Recent research on the fate and transformation of pesticides in the environment has pointed out the need for including more and more polar analytes in multiresidue analysis. Liquid chromatography have been shown to be suitable for mu l t i residue sep a ration of many compounds over a wide ra n ge of polarity without prev i o u s derivatization. Examples can be found in the literature, the most impressive one being the multiresidue separation of 72 pesticides in one run published by Di Corcia and Marchetti some time ago [1]. However, despite the advances in separation and quantifi c ation tech n i q u e s , no sample can be directly analyzed and a multiresidue extraction is a compulsory step in the analytical procedure.In recent years, enrichment of trace compounds on suitable sorbents has been shown to be an interesting alternative to LLE, and has now become a reliable and useful tool for sample handling. In addition, many modern pesticides and identified degra d ation products are fa i rly soluble in water and are therefore less amenable to solvent extraction. Automation and new trends in SPEThe solid-phase extraction (SPE) area has been very active these past years, certainly due to the now well-recognized trends for using solvent-free methods in environmental analytical laboratories and for its suitability to automation [2]. The four individual steps of a typical SPE sequence-i) conditioning of the sorbent, ii) application of the sample, iii) rinsing and cleaning of the sample, and iv) desorption and recovery of the analytes to be separated-can be performed sequentially for up to 24 cartridges at the same time using extraction units working under positive or negative pressure. The whole sequence can also be easily automated with devices now available by several companies using any comm e rcial cart ri d ges or ex t raction disks. Examples are the ASPEC from Gilson, Microlab from Hamilton, AutoTrace and RapidTrace from Zymark. Possibility exists for some of these devices for automatic injection of an aliquot of the final extract into the chromatographic system. The complete automation also exists which couples SPE with direct online LC analysis (ASPEC XL from Gilson, Prospekt from Spark Holland, OSP-2 from Merck). These last two apparatus improved productivity since the next sample is automatically prepared while the previous sample is being analyzed. Th e re fo re, method development can easily be automat e d with various degrees of automation.Off-line SPE materials are mainly disposable cartridges and disk membranes. Besides automation, two other main SPE characteristics have been commercially developed. The first one tends to increase the sample thoughput and the second one to broaden the polarity range of analytes to extract. R e s t ricted fl ow rates and cl ogging are often observe d when handling water containing suspended solids such as surface water. Various approaches have been developed to solve this problem. One consists in depth filters which can be placed above the cartridge or membrane extracti...

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“…The fit is poor, but is only marginally improved by removing five solutes that least fit the model (r = 0.939, S E = 0.25, F = 96 and n = 43); since this action hardly changes the system constants, it is not worthwhile. The factors contributing to retention on the solvated porous graphitic carbon are the ease of cavity formation and general dispersion interactions (m constant) and (HL) octadecylsiloxane-bonded, silica-based sorbent with a high carbon loading; 30 C 18 (LL) octadecylsiloxane-bonded, silica-based sorbent with a low carbon loading 10 ; C 4 (WP) butylsiloxane-bonded, silica based sorbent with wide pores (30 nm); 10 PLRP-S a styrene-divinylbenzene macroporous polymer 28 ; CN cyanopropylsiloxane-bonded, silica-based sorbent 11 ; and DIOL spacer-bonded propanediol, silica-based sorbent. 12 favorable lone pair electron attraction (r constant) opposed by favorable solute hydrogen-bond acid interactions in methanol.…”

Section: Isolation and Separation Of Organic Compounds On Porous Grap...mentioning

confidence: 99%

“…The solvation parameter model was shown to be a powerful tool for identifying the fundamental basis of retention in liquid chromatography and solid-phase extraction. [10][11][12][13][14] Abraham and co-workers [15][16][17] have used this model to study the adsorption of organic compounds from the gas phase at room temperature by Carbotrap (a graphitized carbon black), graphite flakes and fullerene. In each case dispersion interactions were predominantly responsible for retention with a significant contribution from dipole-type interactions.…”

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confidence: 99%

Retention of Neutral Organic Compounds From Solution on Carbon Adsorbents

Poole¹,

Poole²

1997

Anal. Commun.

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Influence of solvent effects on retention in reversed-phase liquid chromatography and solid-phase extraction using a cyanopropylsiloxane-bonded, silica-based sorbent

Cited by 18 publications

References 31 publications

Influence of Composition on the Selectivity of a Mixed-micellar Buffer in Micellar Electrokinetic Chromatography

Influence of Composition on the Selectivity of a Mixed-micellar Buffer in Micellar Electrokinetic Chromatography

Multiresidue solid-phase extraction for trace-analysis of pesticides and their metabolites in environmental water

Retention of Neutral Organic Compounds From Solution on Carbon Adsorbents

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