Influence of solvent on the antioxidant and antimicrobial properties of walnut (Juglans regia L.) green husk extracts

Fernández-Agulló, Adela; Pereira, Eliana; Freire, M. Sonia; Valentão, Patrı́cia; Andrade, Paula B.; González‐Álvarez, Julia; Pereira, José Alberto

doi:10.1016/j.indcrop.2012.05.021

Cited by 273 publications

(223 citation statements)

References 39 publications

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“…The extractive yield was minimum in PE, EA, and acetone extracts in all the five plants. The results support the idea that the solvent greatly affects the extractive yield, antimicrobial and antioxidant activity as also reported by Fernandez-Agullo et al, [17], Chanda et al, [18], Al-Farsi and Lee, [19] and Ammar et al, [20].…”

Section: Extractive Yieldsupporting

confidence: 90%

Evaluation of Antimicrobial Potential of Different Solvent Extracts of Some Medicinal Plants of Semi-Arid Region

Padalia

Rathod

Chanda

2017

Asian J Pharm Clin Res

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Objective: Infections caused by microorganisms that have become resistant to commonly used antibiotics have become a major nuisance globally. The problem of microbial resistance is increasing rapidly, and therefore there is an urgent need to develop novel antimicrobial agents from a natural source. The aim of the present study was to evaluate the antimicrobial activity of different solvent extracts of aerial part of Alysicarpus procumbens, Fimbristylis dichotoma, Saccharum spontaneum, Suaeda nigra, and Typha angustifolia against pathogenic microorganisms. Methods:The extraction was done by individual cold percolation method using five solvents of different polarity, viz., petroleum ether, ethyl acetate, acetone, methanol, and water (aqueous). The antimicrobial activity was done by agar well diffusion method against Gram-positive and Gram-negative bacteria and fungi.Results: All the plant solvent extracts showed varied level of antimicrobial activity against different microorganisms. All extracts of five plants showed better antibacterial activity than antifungal activity; Gram-positive bacteria were more susceptible than Gram-negative bacteria. Conclusion:The polarity of solvent greatly influences extractive yield and antimicrobial activity of medicinal plants. The best activity was shown by solvent extracts of S. nigra. Hence, it can be considered as good source of antimicrobial agents.

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Section: Extractive Yieldsupporting

confidence: 90%

Evaluation of Antimicrobial Potential of Different Solvent Extracts of Some Medicinal Plants of Semi-Arid Region

Padalia

Rathod

Chanda

2017

Asian J Pharm Clin Res

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“…lowers in comparison with methanol, ethanol or water. While in walnut (Juglans regia L.) green husks, the highest extraction yield of polyphenols (44.1%) was obtained when water was used as extraction solvent [60]. By other hand, in a recent study [61], it was found that aqueous and organic solvent have a higher extraction eiciency than absolute organic solvents.…”

Section: Classical Solvent Extractionmentioning

confidence: 98%

“…The diference between solvents resides in their polarity (Figure 1) which afects their capacity in extract phytochemicals. The miscibility of organic solvents (Figure 2) with each other's or even other types of solvents is another fact to be considered in order to improve the polyphenol extraction yield as shown by several studies [59][60][61][62][63].…”

Section: Classical Solvent Extractionmentioning

confidence: 99%

Phenolics in Foods: Extraction, Analysis and Measurements

Aires¹

2017

Phenolic Compounds - Natural Sources, Importance and Applications

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The increasing consumers demands to acquire healthier fruits and vegetables as well as the urgency in looking to natural compounds with antioxidant activity and enhanced antimicrobial activity against antibiotic-resistant pathogenic bacterial strains have encouraged a quick expansion of research studies about enhanced phenolic extraction and identiication methods. Considering the importance of phenolics as natural compounds with antioxidant and antimicrobial activity, this chapter aims to present the most updated information about extraction methods, ranging from the traditional to the most advanced processes, as well as the access to the modern methods used in the identiication and quantiication of phenolics. The main goal of this chapter is to provide the reader with a broad view on the diferent protocols used to extract, identify and quantify phenolic compounds from diferent kinds of foods, including fruits and vegetables.Keywords: phytochemicals, extraction, determination, colorimetric methods, HPLC, HPLC-MS IntroductionThe growing resistance of pathogenic bacterial isolates against the traditional chemical antibiotics as well as the resurgent of old disappeared diseases associated with the constant consumers' demanding of healthier, nutritious and safe food has led the researchers to focus on searching for new, safe and efective molecules. One class of such molecules is the class of polyphenols. Polyphenols are a ubiquitous class of compounds largely present in plants as their secondary metabolites, which are synthesized during their normal development [1] in response to several stressful biotic and abiotic factors [2,3]. This class of compounds are a much diversiied group derived from the amino acids phenylalanine and tyrosine and The results from the last decade's research have shown that polyphenols have important beneicial properties for human health, including antioxidative, antiaging, antibacterial and antimutagenic [7][8][9][10][11]. Moreover, the recent evidence of their interaction with proteins, DNA and other biological molecules has enhanced their exploitation for the production of new natural product-derived therapeutic agents. Despite these advantages, several limitations still persist, particularly those related with their extraction eiciency, which afects the large-scale use of some of these substances. The diiculties in screening, extracting, separation and purifying these compounds have increased the development of new and modern methods to address these limitations. In this context, the aim of this chapter is to present an updated review about sources, technologies and methods that have been developed until now to improve the extraction, detection, separation and full characterization of such beneicial compounds, with special emphasis to their possible application in the design of nutraceuticals and functional food products. Foods as natural resources of phenolicsPolyphenols have been exhaustively studied in their diferent natural matrices such as fruits, vegetables, teas, algae a...

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“…Extraction is a common method for the isolation of natural antioxidants and it is mainly performed with organic solvents (Vázquez et al 2008, Aspé and Fernández 2011, Fernández-Agulló et al 2013, Ramos et al 2013. Although this procedure is efficient and solvents such as ethanol are GRAS (generally recognized as safe), the extracts from other solvents are generally not safe for human consumption due to potentially toxic effects of residual solvents (Salic et al 2011).…”

Section: Introductionmentioning

confidence: 99%

Application of aqueous two phase systems based on polyethylene glycol and sodium citrate for the recovery of phenolic compounds from Eucalyptus wood

Xavier¹,

Freire²,

Vidal³

et al. 2015

Maderas, Cienc. tecnol.

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This paper proposes an alternative way to intensify the exploitation of Eucalyptus wood wastes before valorisation for energy production. An aqueous two-phase system (ATPS) based on PEG 2000 and sodium citrate was investigated for the recovery of phenolic compounds that could act as natural antioxidants for applications including cosmetics, pharmaceuticals, food additives and other industrial applications. The influence of the tie line length (TLL) (26,1-46,1%), extraction temperature (25-65ºC), extraction time (90-390 min) and phase settlement time (1-8 h) were studied. Phenolic compounds were concentrated preferentially in the PEG-rich phase. A partition coefficient of 38 and a total phenols yield of 1,29 mg gallic acid equivalent/100 mg wood dry basis were obtained under the operational conditions selected: TLL, 46,1%, temperature 65ºC, extraction time 90 min and settlement time 1 h. Analysis of the extracts by RP-HPLC-ESI-TOF confirmed the presence of various phenolic compounds with demonstrated antioxidant activity: monogalloyl glucose, (-)-gallic acid, ellagic acid and quercetin 3-O-rhamnoside.

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Influence of solvent on the antioxidant and antimicrobial properties of walnut (Juglans regia L.) green husk extracts

Cited by 273 publications

References 39 publications

Evaluation of Antimicrobial Potential of Different Solvent Extracts of Some Medicinal Plants of Semi-Arid Region

Evaluation of Antimicrobial Potential of Different Solvent Extracts of Some Medicinal Plants of Semi-Arid Region

Phenolics in Foods: Extraction, Analysis and Measurements

Application of aqueous two phase systems based on polyethylene glycol and sodium citrate for the recovery of phenolic compounds from Eucalyptus wood

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