Influence of some heavy metals on growth, alkaloid content and composition in Catharanthus roseus L.

Abstract

Shoot biomass production, alkaloid content and composition as influence by cadmium, manganese, nickel and lead at uniform dose of 5 mM were investigated in Catharanthus roseus plants grown in sand culture. Treatment with Mn, Ni, and Pb significantly enhanced total root alkaloid accumulation. Cd and Ni treatment resulted in two-fold where as Pb treatment resulted in three fold increase in serpentine content of roots. The non-significant affect on biomass suggests that plants can withstand metal stress at the level tested with positive affect on root alkaloid content.

Effect of cobalt nanoparticles and cobalt ions on alkaloids production and expression of CrMPK3 gene in Catharanthus roseus suspension cultures

“…Alkaloids accumulation recorded following stressful Co 2+ treatments is a defense response against oxidative stress (13). It was recorded in C. roseous following exposure to different types of stress including heavy metals (14)(15)(16)(17), drought (53) and fungal attack (54).…”

“…As a consequence, the biosynthesis of reduced compounds including isoprenoids, phenols or alkaloids, is enhanced (13). The potentialities of heavy metals in enhancing alkaloids production in C. roseus were recorded using Cd (14), Mn, Ni, and Pb (15), Hg (16) and Cr (17).…”

Evaluation of Phytoremediation Potential of <i>Catharanthus roseus</i> with Respect to Chromium Contamination

“…Consequently, one of the aims of this study was also to examine whether Cr induced stress affects the antioxidant defense system, as well as the accumulation of alkaloids in C. roseus. The genus Catharanthus has gained considerable reputation in the therapeutic world for its wide assemblage of over 100 alkaloids including vincristin, vinblastin, ajmaline, ajmalicine and serpentine which are extremely important [13] [14]. The plant, though can be cultivated in gardens as a flowering plant, is known for its robust growth in wastelands and is toxic due to the presence of toxic alkaloids.…”

A Brassica napus Reductase Gene Dissected by Associative Transcriptomics Enhances Plant Adaption to Freezing Stress

“…So far, definitions of alkaloids are generally focused on strong pharmacological effects, such as antimitotic, antidote, anticancer, and antioxidants (Schlager and Drager, 2016). The concentration of alkaloid compounds is predominantly inducible when plants are subjected to multiple stresses (Srivastava and Srivastava, 2010;Cheng et al, 2018). However, few studies have recognized the positive correlations between alkaloids and stress resistance.…”

“…Alkaloid is one of the major secondary metabolites that is inducible under unfavorable conditions, especially drought stress (Selmar and Kleinwachter, 2013). Heavy metals can also promote the accumulation of alkaloid in Catharanthus roseus L. (Srivastava and Srivastava, 2010). The short-chain dehydrogenase/reductase (SDR) protein, which belongs to the NAD(P)-binding Rossmann-fold superfamily, functions in the biosynthesis of benzylisiquinoline alkaloids (i.e.…”