Influence of steric hindrance on the 1,4- versus 1,6-Michael addition: synthesis of furans and pentasubstituted benzenes

Abstract

We described the influence of steric hindrance on 1,4- versus 1,6-Michael addition reaction on 2-(3,3-bis(methylthio)-1-arylallylidene)malononitriles. An efficient and direct synthesis of trisubstituted furans was achieved through the reaction of 2-(3,3-bis(methylthio)-1-arylallylidene)malononitriles...