Influence of substrates concentrations on the dynamics of oxygen demand and aeration performance in ideal bioreactors

Ahmed, Ahmed Shawki; Rosso, Diego; Santoro, Domenico; Nakhla, George

doi:10.1016/j.psep.2021.07.033

Cited by 3 publications

(2 citation statements)

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“…However, change the environment temperature and solute is not ideal strategies due to strict biocatalysis conditions. Moreover, if oxygen‐enriched ventilation is used to increase the oxygen partial pressure, it is necessary to establish an oxygen‐enriched air preparation device, significantly increasing the operating cost 27 . Overall, the C * parameter is basically constant in the conventional biocatalysis process.…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, if oxygen-enriched ventilation is used to increase the oxygen partial pressure, it is necessary to establish an oxygen-enriched air preparation device, significantly increasing the operating cost. 27 Overall, the C* parameter is basically constant in the conventional biocatalysis process. Therefore, increasing K L α in the industry is the main method to intensify OTR.…”

Section: Introductionmentioning

confidence: 99%

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Gas pressure intensifying oxygen transfer to significantly improving the bio‐oxidation productivity of whole‐cell catalysis

et al. 2022

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Oxygen, as a terminal electron acceptor, is an essential substrate in the aerobic biooxidation process, affecting bacterial vitality and bio-oxidation performance. In this study, a newfangled platform biotechnology of sealed-oxygen supply bioreactor (SOS-BR) was developed by improving gas pressure to significantly intensify oxygen transfer rate to resolve the formidable barriers of aerobic catalysis. In virtue of SOS-BR, the bio-productivity was greatly improved for three representative substrates (xylose, furfural, and glycerol) bio-oxidation with the whole-cell catalysis of Gluconobacter oxydans. The determination of oxygen transfer coefficient (K L α) established an upgraded theoretical dynamic model for gas pressure intensification biosystem. Additionally, viscosity measurement and combined pressure control strategy explained the inflection point phenomenon of productivity and confirmed the intensify mechanism. The smart strategy of significantly intensifying oxygen transfer provided insightful ideas for overcoming the stubborn obstacle of obligate aerobic catalysis, and further promoted the development and industrial practicability of bio-oxidation.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%