Influence of Temperature on the Measuring Accuracy of Devices Based on Surface Plasmon Resonance Phenomenon

Dorozinska, Hanna; Turu, Tatyana A.; Маркіна, О. М.; Dorozinsky, Glib; Maslov, V. P.

doi:10.4236/mi.2018.71001

Cited by 10 publications

(3 citation statements)

References 18 publications

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“…It should be mentioned that the effect of temperature is one of the important factors determining the accuracy of measurements. As it is known, it determines a lot of the dimensional errors of the measurement result [48]. Moreover, the temperature substantially affects the material parameters of the sensor elements.…”

Section: Discussionmentioning

confidence: 99%

Comparison of the Optical Planar Waveguide Sensors’ Characteristics Based on Guided-Mode Resonance

et al. 2020

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A comparison of optical sensors’ characteristics based on guided-mode resonance has been carried out. It was considered a prism structure with a metal film, a metal grating on a metal substrate and a dielectric grating on a dielectric substrate. It is shown that the main characteristics are determined by the sensitivity of the constant propagation of the respective waveguides on a change in wavelength and a change in the refractive index of the tested medium. In addition, they depend on the full width at half maximum of the spectral or angular reflectance dependence. The corresponding analytical relationships obtained for the three types of sensors are almost the same. It is demonstrated that the ratio of the sensor spectral sensitivity on the resonance curve spectral width is equal to the ratio of the angular sensitivity on the angular width of the corresponding resonance curve for all three types of sensors.

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Section: Discussionmentioning

confidence: 99%

Comparison of the Optical Planar Waveguide Sensors’ Characteristics Based on Guided-Mode Resonance

et al. 2020

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“…The signal on the sensorgram must form a stable baseline. External influences that cause signal fluctuations in the sensorgram, such as temperature, must be minimized to be as small as possible [34]. Once a baseline is obtained, the solution containing the analyte can be injected.…”

Section: Principle Of Spr Kineticsmentioning

confidence: 99%

Unraveling the Dynamics of SARS-CoV-2 Mutations: Insights from Surface Plasmon Resonance Biosensor Kinetics

Nurrohman,

Chiu

2024

Biosensors

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Surface Plasmon Resonance (SPR) technology is known to be a powerful tool for studying biomolecular interactions because it offers real-time and label-free multiparameter analysis with high sensitivity. This article summarizes the results that have been obtained from the use of SPR technology in studying the dynamics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutations. This paper will begin by introducing the working principle of SPR and the kinetic parameters of the sensorgram, which include the association rate constant (ka), dissociation rate constant (kd), equilibrium association constant (KA), and equilibrium dissociation constant (KD). At the end of the paper, we will summarize the kinetic data on the interaction between angiotensin-converting enzyme 2 (ACE2) and SARS-CoV-2 obtained from the results of SPR signal analysis. ACE2 is a material that mediates virus entry. Therefore, understanding the kinetic changes between ACE2 and SARS-CoV-2 caused by the mutation will provide beneficial information for drug discovery, vaccine development, and other therapeutic purposes.

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“…Оскільки з часом металева плівка деградує під впливом досліджуваних речовин, особливо у агресивних середовищах, рівень відгуку такої конструкції зменшується [17].…”

Section: модель кречманаunclassified

Effect of the Thickness of Nanoscale Layers of the Metal-Dielectric Structure on Its Optical Characteristics

Hetmanchuk

Machulianslyi

2022

Microsyst., Electron. & Acoust.

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A biosensor is a device which uses a mixture of biological and physicochemical components to detect molecular-level interactions. Essentially, biosensors detect the change in physical properties which occur when an immobilized biological molecule, such as an antibody or a protein, binds to their target analyte. A number of methods have been developed to determine interactions between bioreceptors and their analytes, many of which are based on the principle of Surface Plasmon Resonance, or SPR. The ubiquity of SPR comes from its inherent advantages; it allows real time, highly sensitive monitoring of a wide range of molecular interactions, without the requirement for additional labelling of samples. Surface Plasmon Resonance is caused by the interaction of electromagnetic radiation and the free-flowing cloud of electrons within a metal, a process which induces electromagnetic waves and, under certain conditions, resonance effects. Alterations in the physical conditions at the surface have a significant effect on this resonance, and the detection of these changes form the basis of the SPR biosensor. In the work, the effect of the thickness of the layers of the metal-dielectric structure on its optical characteristics was studied. The simulation was carried out for the Krechman configuration, which is a glass prism on which a multilayer metal-dielectric structure is applied. AuSiO2 was used as a metal-dielectric structure, and a laser beam with a wavelength of 633 nm was used as a source of external electromagnetic radiation. The thickness of the gold film varied from 1 to 60 nanometers. The lowest value of the reflection coefficient is reached at a thickness of 50 nm. The thickness of the silicon dioxide film varied from 1 to 30 nm. When the thickness of the dielectric layer is up to 10 nm, its influence on the optical characteristics is insignificant. Macroscopic values of parameters were used in the study, but it is known that real parameters differ greatly from macroscopic ones. To increase the accuracy of modeling the sensor element in further studies, it will be necessary to take into account dimensional changes in the optical parameters of the nanosized metal component in the structure of the sensor element.

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Influence of Temperature on the Measuring Accuracy of Devices Based on Surface Plasmon Resonance Phenomenon

Cited by 10 publications

References 18 publications

Comparison of the Optical Planar Waveguide Sensors’ Characteristics Based on Guided-Mode Resonance

Comparison of the Optical Planar Waveguide Sensors’ Characteristics Based on Guided-Mode Resonance

Unraveling the Dynamics of SARS-CoV-2 Mutations: Insights from Surface Plasmon Resonance Biosensor Kinetics

Effect of the Thickness of Nanoscale Layers of the Metal-Dielectric Structure on Its Optical Characteristics

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