Influence of the complex of retinol–vitamin C on skin surface lipids

Wójcik, Aneta; Bartnicka, Ewelina; Namieciński, Piotr; Rotsztejn, Helena

doi:10.1111/jocd.12140

Cited by 8 publications

(6 citation statements)

References 19 publications

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“…Furthermore, vitamin A is an important constituent of the epidermis, which contributes to the correct physiological functioning of the skin, especially it affects surface lipids and increases skin regeneration [22]. Nutritional deficiencies, lack of exposure to sunlight and excessive oxidative stresses can be causes of vitamin A deficiency.…”

Section: Discussionmentioning

confidence: 99%

Improving Skin Aging, Skin Hydration and Sensitive Skin with Four Specific Skin Care Products: Results from a Single-Centre, Observational, Prospective Study

Piccioni¹,

García-Rodrigo²,

Pellegrini³

et al. 2017

JCDSA

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In this study, we assessed the efficacy and safety of four skin care products indicated for skin hydration (Aqua Therapy  and Perfecta ) and are formulated with a specific combination of active compounds (Dermo28  ). Evaluation of sebum secretion, hydration and pH of the skin (all groups), wrinkle severity (Unica Resurfacing Therapy  ) and erythema (Comfort Therapy  ) was performed at baseline and after 4 weeks of treatment. A significant increase in hydration was recorded in subjects with dry skin receiving Aqua Therapy  for facial hydration and Perfecta  for body hydration, respectively (p < 0.001 for both). A significant decrease in the modified Fitzpatrick wrinkle scale (p = 0.006) and an increase in sebum secretion and hydration (p = 0.013 and p < 0.001, respectively) were observed in the Unica Resurfacing Therapy  group. In subjects with sensitive skin (Comfort Therapy  ), a decrease in erythema (p = 0.012), an increase in sebum secretion (p = 0.001) and hydration (p < 0.001), and a reduction in pH (p = 0.005) were detected at the end of treatment. Only one patient reported a minor adverse event. This specific combination of active ingredients was clinically effective and safe, and contributed to skin surface hydrolipidic film regeneration, improvement of wrinkle depth and reduction of redness.

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Section: Discussionmentioning

confidence: 99%

Improving Skin Aging, Skin Hydration and Sensitive Skin with Four Specific Skin Care Products: Results from a Single-Centre, Observational, Prospective Study

Piccioni¹,

García-Rodrigo²,

Pellegrini³

et al. 2017

JCDSA

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“…Te 2% retinol chemical peel was applied 3 times in 3 weeks of intervals in 21 women. However, there was no other parameter investigated besides sebum secretion [22]. In another study by Sadick et al, 24 patients (photodamage group, n � 14 (with an acne subgroup, n � 5]; melasma group, n � 5; skin of color, n � 5) were treated with 3% retinol peel in 6 weeks of intervals and a series of 2-4 peels.…”

Section: Discussionmentioning

confidence: 99%

Unique Retinol Therapy with Antioxidant and Anti‐Inflammaging Complex for Naturally Reborn Skin: The Clinical Case Series Study

Sołdacka,

Podgórska,

Barańska-Rybak

2023

Dermatologic Therapy

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One of the methods used to prevent symptoms of skin aging are chemical peels. Among retinoids, retinol is much less described in the literature than tretinoin as a substance used in the peel procedure. The aim of our study was to determine the efficacy of using a 4% retinol solution product containing novel TGF-β activators and antioxidants in improving the condition of the skin in patients with facial skin issues caused by aging and skin disorders. Each of 15 patients went through three peel treatment series, with a 30-day gap between each session and was examined using Multi Skin Test MC 1000 Courage + Khazaka, evaluating hydration, elasticity, and skin pigmentation and Observ 520x. All patients reported overall improvement after the peeling procedure, and most of them reported subjective improvement in the reduction of the facial skin: tone, skin pigmentation, dehydration, dryness, structure, and sebaceous gland activity. An objective evaluation revealed significant clinical improvement in pigmentation in study groups. Elasticity parameters were shown to increase during treatment, with a greater effect occurring in patients with mature skin with first signs of aging and patients with postinflammatory hyperpigmentation, atrophic acne scars, and enlarged pores. Concluding, combined peel therapy of 4% retinol serum product containing novel TGF-β activators and antioxidants showed good efficacy in reducing facial pigmentation of the skin high patients’ satisfaction with the procedure. The study revealed that the described method is simple to use, has low cost, is with rare adverse events, and has well tolerability.

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“…The corneometric and sebumetric methods that we used are the reference methods. In the literature, they are mainly used to: compare other methods to them [52,53], the impact of supplementation (e.g., collagen [54], evaluation of the effectiveness of new formulations and uses of ingredients [55][56][57] and the external use of preparations [58][59][60][61]). To our knowledge, this is the first time that they have been used to comprehensively assess the impact of a diet on skin hydration and lubrication.…”

Section: Discussionmentioning

confidence: 99%

Intake of Antioxidant Vitamins and Minerals in Relation to Body Composition, Skin Hydration and Lubrication in Young Women

et al. 2021

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The aim of this study was to estimate the consumption of selected dietary components with antioxidant properties, undertake body composition analysis, assess skin hydration and lubrication, and establish the relationships between the above parameters. The study was carried out on 172 young women. The consumption of ingredients (vitamins A, C, D and E, and Cu, Mn, Zn) was assessed using the Diet 6.0 program, body composition was assessed using electrical bioimpedance and skin hydration and lubrication were assessed using the corneometric and sebumetric methods, respectively. About one-third of students showed insufficient consumption of vitamin C, vitamin E and zinc, while about 99% showed insufficient vitamin D levels. The highest degree of hydration was observed in the areas of the eyelids, neckline and chin. The greatest amount of sebum was found in the area of the nose and forehead. Low positive correlations between hydration or lubrication and Cu, vitamin A and vitamin E were observed. In conclusion, to properly moisturize and lubricate the skin, young women should eat products that are rich in ingredients with antioxidant properties, in particular fat-soluble vitamins A and E, but also copper.

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Influence of the complex of retinol–vitamin C on skin surface lipids

Abstract: Retinol peel treatments can help to increase the amount of skin surface lipids in women during menopause.

Cited by 8 publications

References 19 publications

Improving Skin Aging, Skin Hydration and Sensitive Skin with Four Specific Skin Care Products: Results from a Single-Centre, Observational, Prospective Study

Improving Skin Aging, Skin Hydration and Sensitive Skin with Four Specific Skin Care Products: Results from a Single-Centre, Observational, Prospective Study

Unique Retinol Therapy with Antioxidant and Anti‐Inflammaging Complex for Naturally Reborn Skin: The Clinical Case Series Study

Intake of Antioxidant Vitamins and Minerals in Relation to Body Composition, Skin Hydration and Lubrication in Young Women

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