The article considers the results of vibration dynamic tests of the vibration acceleration levels of a vibration insulated reinforced concrete slab and floors of a residential building, which have confirmed the effectiveness of the seismic vibration isolation system using rubber elements. The registered levels of vibration accelerations in residential premises on different floors do not exceed permissible levels according to sanitary standards, which ensures comfortable living conditions in the presence of dynamic influences. To determine the actual vibration levels of the soil and piles vibration and dynamic studies were carried out. Based on the results of these studies, numerical calculations were carried out to determine the compliance of the predicted vibration levels in residential premises with the existing sanitary standards when they are exposed to real anthropogenic loads.