Influence of the menstrual cycle on the incidence of nausea and vomiting after laparoscopic gynecological surgery: a pilot study

Šimurina, Tatjana; Mraović, Boris; Skitarelić, Neven; Andabaka, Tatjana; Sonicki, Zdenko

doi:10.1016/j.jclinane.2011.07.011

Cited by 25 publications

(11 citation statements)

References 21 publications

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“…This was in contrast to a retrospective study which demonstrated that the incidence of nausea and vomiting was higher on the first eight menstrual days (Beattie et al, 1991). A recent prospective study showed that patients in the luteal phase of their menstrual cycle might have a decreased risk of PONV after laparoscopic gynecological surgery in the early postoperative period (Simurina et al, 2012). Coburn et al (1993) showed that the likelihood of vomiting was related to the peak plasma oestradiol level.…”

Section: Discussionmentioning

confidence: 72%

Nausea and Vomiting after Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma: Incidence and Risk Factor Analysis

Wang

Zhu

Vargulick

et al. 2013

Asian Pacific Journal of Cancer Prevention

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Section: Discussionmentioning

confidence: 72%

Nausea and Vomiting after Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma: Incidence and Risk Factor Analysis

Wang

Zhu

Vargulick

et al. 2013

Asian Pacific Journal of Cancer Prevention

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“…In a study performed by Simurina et al [ 17 ] to evaluate the probable effect of the menstrual cycle on the incidence of PONV among Croatian female surgical patients, women in the luteal phase of the menstrual cycle were less likely to suffer from PONV compared to the rest of the study population. In contrast, in another study by Sener et al [ 4 ], performed to investigate the association between various phases of the menstrual cycle with postoperative pain and PONV among Turkish female surgical patients, the frequency of PONV, as well as postoperative pain was highest among women in the luteal and the follicular phases of the menstrual cycle.…”

Section: Discussionmentioning

confidence: 99%

Postoperative pain, nausea and vomiting among pre- and postmenopausal women undergoing cystocele and rectocele repair surgery

Vahabi

Abaszadeh

Yari

et al. 2015

Korean J Anesthesiol

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BackgroundPostoperative nausea and vomiting (PONV) and postoperative pain are among the most common side-effects of surgery. Many factors, such as a change in the level of sex hormones, are reported to affect these complications. This study aimed to evaluate the probable effects of the menopause on PONV and postoperative pain.MethodsProspective study, in which a total number of 144 female patients undergoing cystocele or rectocele repair surgery under standardized spinal anesthesia were included. Patients were divided into two equally sized sample groups of pre- and postmenopausal women (n = 72). The occurrence of PONV, the severity of pain as assessed by visual analog scale (VAS) pain score, and the quantity of morphine and metoclopramide required were recorded at 2, 4, 6, 12, 18 and 24 h after surgery.ResultsThe mean VAS pain score and the mean quantity of morphine required was higher among premenopausal women (P = 0.006). Moreover, these patients required more morphine for their pain management during the first 24 h after surgery compared to postmenopausal women (P < 0.0001). No difference was observed between the two groups regarding the incidence of PONV (P = 0.09 and P = 1.00 for nausea and vomiting, respectively) and the mean amount of metoclopramide required (P = 0.38).ConclusionsPremenopausal women are more likely to suffer from postoperative pain after cystocele and rectocele repair surgery. Further studies regarding the measurement of hormonal changes among surgical patients in both pre- and postmenopausal women are recommended to evaluate the effects on PONV and postoperative pain.

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“…A regular cycle is defined as lasting 23-35 days with no variations in the length of cycle of more than 2 days) [10]. Only patients in the following time intervals were recruited:…”

Section: Inclusion Criteriamentioning

confidence: 99%

“The influence of female body mass index, menstrual cycle phase and age on propofol injection pain”

Mostafa

Kamal

Mohamed

et al. 2021

Egyptian Journal of Anaesthesia

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Background: Eliminating propofol injection pain (PIP) should be multimodal, including pharmacological and non-pharmacological interventions. Understanding risk factors -body mass index, menstrual cycle phase and age for example -leading to increased pain sensitivity will identify patients at most risk for PIP, permitting effective treatment strategies to be initiated at an early stage. Objective: Our goal is to determine occurrence and severity of propofol injection pain among female patients, whether they are obese or non-obese, during different menstrual cycle phases. Methods: Design: A prospective observational study. Setting: Single university teaching hospital's operating rooms. Patients: 84 female undergoing surgeries under general anesthesia, classified as American Society of Anesthesiologists (ASA) physical status I-II, between 18 and 65 years of age were enrolled. Interventions: We evaluated propofol injection pain using visual analogue scale (VAS) during induction of general anesthesia. Main outcome measure: The relation between propofol induced peripheral venous pain and female body mass index, menstrual cycle phase and age. Results: 71.4% of patients experienced PIP. Of those patients who experienced PIP; 40.5% (34/ 84 patients) had moderate to severe pain. Age <35 years was the only independent predictor of moderate/severe PIP (sensitivity 62%, specificity 78%). After adjustment for age category, there was no statistically significant association between occurrence of moderate/severe PIP and obesity or menstruation. Conclusion:Propofol injection pain prophylactic measures should be considered in young females <35 years as they may be more prone to moderate/severe PIP.

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Influence of the menstrual cycle on the incidence of nausea and vomiting after laparoscopic gynecological surgery: a pilot study

Cited by 25 publications

References 21 publications

Nausea and Vomiting after Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma: Incidence and Risk Factor Analysis

Nausea and Vomiting after Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma: Incidence and Risk Factor Analysis

Postoperative pain, nausea and vomiting among pre- and postmenopausal women undergoing cystocele and rectocele repair surgery

“The influence of female body mass index, menstrual cycle phase and age on propofol injection pain”

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