Influence of the Microdroplets Sizes of Magnetic Emulsions on the Magneto-Optical Effect

A Novel Microfluidics Droplet-Based Interdigitated Ring-Shaped Electrode Sensor for Lab-on-a-Chip Applications

“…Benefits of microfluidics technology are based on small volume of liquid samples [10], that enables faster chemical reactions process [11,12] due to acceleration of the mass and heat transfer in the microscale [13,14] and integrated micro actuators [15][16][17]. In the last decades, a microfluidics droplet-based approach has been fast evolved [14,[18][19][20][21], largely employed for biomedical applications [16,22,23], especially leading to studies with cells and antibody development [20,24,25], where microfluidics devices have enabled a creation of new tools and protocols [16,[26][27][28], for example, for single-cell encapsulation, co-encapsulation, cellsorting, droplet recovery/extraction (de-oiling) and pico-injection [14,22,24]. Precise control and detection of droplet generation and size are indispensable in numerous microfluidic applications [29-2 32], particularly in the field of antibody and drug development [7], including manipulation and delivery in these processes, many of which entail the manipulation of cells or beads, inside of microchannels.…”

“…However, it is important to mention that optical-based droplet detection often demands a considerably intricate setup external to the device, involving the introduction of laser light and the subsequent detection of scattered light using optical elements positioned within a microfluidic channel or chamber, as evidenced by studies [12,13]. Optics-based interrogation dependence of external equipment does not allow the fabrication of portable point-of-care (POC) [18,34]. Electrochemical sensors can be relatively easier to manufacture and, depending on the specific use case, enable compact circuitry for small and portable devices [10,35,36].…”

A Novel Microfluidics Droplet-Based Interdigitated Ring-Shaped Electrode Sensor for Lab-on-a-Chip Applications

“…The benefits of microfluidics technology are based on the small volume of liquid samples [ 10 ], which enables faster chemical reactions [ 11 , 12 ] due to the acceleration of mass and heat transfer at the microscale [ 13 , 14 ] and integrated micro actuators [ 15 , 16 , 17 ]. In the last decades, a microfluidics droplet-based approach rapidly evolved [ 14 , 18 , 19 , 20 , 21 ], largely employed for biomedical applications [ 16 , 22 , 23 ], especially leading to studies with cells and antibody development [ 20 , 24 , 25 ], where microfluidics devices have enabled the creation of new tools and protocols [ 16 , 26 , 27 , 28 ], for example, for single-cell encapsulation, co-encapsulation, cell-sorting, droplet recovery/extraction (de-oiling), and pico-injection [ 14 , 22 , 24 ]. The precise control and detection of droplet generation and size are indispensable in numerous microfluidic applications [ 29 , 30 , 31 , 32 ], particularly in the field of antibody and drug development [ 7 ], including manipulation and delivery in these processes, many of which entail the manipulation of cells or beads inside microchannels for the precise generation and monitoring of microdroplets [ 8 ], for which it is necessary to integrate sensing and microfluidics channels [ 33 ].…”

“…However, it is important to mention that optical-based droplet detection often demands a considerably intricate setup external to the device, involving the introduction of laser light and the subsequent detection of scattered light using optical elements positioned within a microfluidic channel or chamber, as evidenced by studies [ 12 , 13 ]. Optics-based interrogation dependence on external equipment does not allow for the fabrication of portable point of care (POC) [ 18 , 37 ]. Electrochemical sensors can be relatively easy to manufacture and, depending on the specific use case, enable compact circuitry for small and portable devices [ 10 , 38 , 39 ].…”