Influence of the purification of human adult pancreatic islets on insulin secretion

Abstract

Although during purification process islets were exposed to a number of insults that might result in cellular damage and functional impairment, our assessments showed that islets in P cultures preserved their functional capacity better than islets in NP cultures, since they had greater insulin secretion.

Effects of bacterial infection on insulin secretory capacity of human adult pancreatic islets

“…Like most members of the Enterobacteriaceae, these organisms are capable of causing opportunistic infection in hospitalised or debilitated patients. 18 Staphylococcus aureus is considered an extracellular pyogenic pathogen and in tissue is found almost exclusively in extracellular spaces. surfaces, and ii) elaborate proteases, exotoxins and enzymes that destroy tissue and protect bacteria from the host immune response.…”