Structural designers that design buildings use different criteria to select the frames’ materiality and structural solutions. Very often, the primary test is the cost of construction. Sometimes, solutions are determined by the terms of structure, architectural preferences, technological needs, fire safety requirements, environmental conditions, exploitation costs over the life of the building, ecological aspects, and experience, etc. This paper proposes an approach for analyzing the structural elements of buildings taking into account the impact on the environment using jointly incorporating subjective and objective aspects. The objective to combine the most important criteria into a single unit and carry out the overall assessment could be done by giving each variable a weighted value and perform a so-called multi-criteria analysis. This article shows the efficiency of the structural solution of the one-story building. The case study presents an investigation and comparison of five possible symmetrical structural solutions by multi-criteria assessment methods: The analysis of three steel frameworks differs majorly due to the beam-column characteristics, as well as precast RC frame structures case and combined steel beams and RC columns frame option. Possible solutions must meet all the essential requirements of the building, including mechanical resistance and stability. The obtained results show a broad assessment of the structural solutions of the building.