Influence of the Sense of Coherence, the Doctor–Patient Relationship, Optimism and Non-Haematological Adverse Reactions on Health-Related Quality of Life in Patients with Breast Cancer

Prieto-Callejero, Blanca; Rivera, Francisco; Andrés-Villas, Montserrat; Gómez‐Salgado, Juan

doi:10.3390/jcm8122043

Cited by 4 publications

(3 citation statements)

References 30 publications

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“…Breast cancer chemotherapies harm the quality of life 17 , 32 even though it increases overall survival (OS) and disease-free survival (DFS). 33–36 As a result, understanding the effect of breast cancer treatment on patients’ quality of life has been the central clinical and research question.…”

Section: Discussionmentioning

confidence: 99%

The Impact of AC and AC-T Chemotherapy’s Toxicities on Quality of Life Among Women with Breast Cancer in Ethiopia: A Prospective Patient-Reported Outcomes Study

Gadisa

Wang

Yimer

2021

BCTT

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Purpose The study aimed to evaluate the quality of life patterns and the effects of AC and AC-T chemotherapy’s toxicities on QoL among Ethiopian women with breast cancer. Methods QoL was measured at baseline and at every end of two cycles, for the median of 8 cycles among 146 breast cancer women on AC and AC-T chemotherapy, using EORTC QLQ-C30 and BR23 instruments. The effect of QoL score, socio-demographic, and clinical variables at baseline were adjusted for the effect of chemotherapy’s toxicities on QoL. Results Overall QoL, all functional scales (except cognitive functioning, body image, future perspectives, and sexual functioning) and symptom scales (except dyspnea, insomnia, pain score, arm, and breast symptoms) of EORTC QLQ-C30 and BR23 deteriorated significantly both clinically and statistically, in particular, during the first two cycles of chemotherapy. After the end of cycle 2 or 4, except for cognitive, social functioning, and financial difficulties of the patients, almost all other QoL dimensions were improved towards pretreatment score by the end of cycle 8. In addition to age, educational status, and tumor stage, the Global Health Status (−10.55≤B≤−7.71, P≤0.013), and the functional scales (−25.320≤B≤−6.351, P≤0.033) of EORTC QLQ-C30 and BR23 were significantly affected at least by one of the AC and AC-T chemotherapy’s toxicity such as grade≥2 fatigue, dysgeusia, constipation, dry mouth, vomiting, oral mucositis, skin hyperpigmentation and/or peripheral neuropathy than their lower grade. Grade≥2 fatigue, dysgeusia, oral mucositis, constipation, peripheral neuropathy, anemia arthralgia/myalgia, dry mouth, diarrhea, constipation, and/or skin hyperpigmentation were positively predicted for the deterioration of symptoms scale of EORTC QLQ-C30 and BR23 (4.819≤B≤26.451, P≤0.043). Conclusion Quality of life among Ethiopian breast cancer patients on AC and AC-T regimens significantly deteriorated particularly during the first two cycles of chemotherapy. In addition to the age, tumor stage and educational status of the patients, grade≥2 fatigue, dysgeusia, constipation, oral mucositis, dry mouth, peripheral neuropathy, and skin hyperpigmentation due to AC and AC-T chemotherapy were frequently associated with deterioration of different scales/items QoL. Hence, devising different strategies to improve the deteriorated QoL due to chemotherapy’s toxicities particularly during the first two cycles has paramount importance.

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Section: Discussionmentioning

confidence: 99%

The Impact of AC and AC-T Chemotherapy’s Toxicities on Quality of Life Among Women with Breast Cancer in Ethiopia: A Prospective Patient-Reported Outcomes Study

Gadisa

Wang

Yimer

2021

BCTT

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“…Prieto-Callejero [31] found that higher levels of optimism were associated with higher levels of SOC in breast cancer patients (β=0.49,P<0.05) and higher levels of pessimism were associated with lower levels of SOC (β=-0.24,P<0.05). Some studies have shown [32] that patients with high SOC are more likely to be attracted to positive emotional stimuli in their environment and less likely to perceive stressful stimuli, and are more likely to maintain an optimistic state, while patients with low SOC appear relatively stable avoidance of positive emotions, focus more on negative information, and have difficulty de-attending to negative emotions, ultimately suffering from a pessimistic state.…”

Section: Optimism and Pessimismmentioning

confidence: 96%

“…Sense of coherence (SOC), as a positive psychological resource, reflects an individual's attitude to life and ability to use support resources when coping with stress [3] . Research [4] has shown that a high level of SOC in breast cancer patients can help patients to face the disease with a positive attitude, use various support resources flexibly, buffer stress effectively, reduce the occurrence of anxiety and depression, and improve the quality of life, which is important for promoting patients' physical and mental health. However, there are relatively few studies on SOC for breast cancer patients.…”

Section: Introductionmentioning

confidence: 99%

Research Progress of Breast Cancer Patients' Sense of Coherence

2022

AJMHS

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According to the latest data from the World Health Organization's Agency for Research on Cancer, breast cancer has replaced lung cancer as the most prevalent disease in the world, and the incidence rate is increasing year by year, with the incidence population becoming younger and younger. Patients often experience surgery, chemotherapy and other treatments, and often have anxiety, depression and other adverse emotions, which reduce the treatment effect and seriously affect the quality of life. The Sense of Coherence is a protective psychological resource that can effectively buffer stress and maintain physical and mental health. Therefore, this paper reviews the concept and measurement tools, and the current situation of sense of coherence in breast cancer patients, and the influencing factors, in order to provide reference for clinical research on improving breast cancer patients' sense of coherence level in China.

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Chronic kidney disease, female infertility, and medically assisted reproduction: a best practice position statement by the Kidney and Pregnancy Group of the Italian Society of Nephrology

Attini,

Cabiddu,

Ciabatti

et al. 2023

J Nephrol

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Fertility is known to be impaired more frequently in patients with chronic kidney disease than in the general population. A significant proportion of chronic kidney disease patients may therefore need Medically Assisted Reproduction. The paucity of information about medically assisted reproduction for chronic kidney disease patients complicates counselling for both nephrologists and gynaecologists, specifically for patients with advanced chronic kidney disease and those on dialysis or with a transplanted kidney. It is in this context that the Project Group on Kidney and Pregnancy of the Italian Society of Nephrology has drawn up these best practice guidelines, merging a literature review, nephrology expertise and the experience of obstetricians and gynaecologists involved in medically assisted reproduction. Although all medically assisted reproduction techniques can be used for chronic kidney disease patients, caution is warranted. Inducing a twin pregnancy should be avoided; the risk of bleeding, thrombosis and infection should be considered, especially in some categories of patients. In most cases, controlled ovarian stimulation is needed to obtain an adequate number of oocytes for medically assisted reproduction. Women with chronic kidney disease are at high risk of kidney damage in case of severe ovarian hyperstimulation syndrome, and great caution should be exercised so that it is avoided. The higher risks associated with the hypertensive disorders of pregnancy, and the consequent risk of chronic kidney disease progression, should likewise be considered if egg donation is chosen. Oocyte cryopreservation should be considered for patients with autoimmune diseases who need cytotoxic treatment. In summary, medically assisted reproduction is an option for chronic kidney disease patients, but the study group strongly advises extensive personalised counselling with a multidisciplinary healthcare team and close monitoring during the chosen medically assisted reproduction procedure and throughout the subsequent pregnancy. Graphical abstract

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Influence of the Sense of Coherence, the Doctor–Patient Relationship, Optimism and Non-Haematological Adverse Reactions on Health-Related Quality of Life in Patients with Breast Cancer

Cited by 4 publications

References 30 publications

The Impact of AC and AC-T Chemotherapy’s Toxicities on Quality of Life Among Women with Breast Cancer in Ethiopia: A Prospective Patient-Reported Outcomes Study

The Impact of AC and AC-T Chemotherapy’s Toxicities on Quality of Life Among Women with Breast Cancer in Ethiopia: A Prospective Patient-Reported Outcomes Study

Research Progress of Breast Cancer Patients' Sense of Coherence

Chronic kidney disease, female infertility, and medically assisted reproduction: a best practice position statement by the Kidney and Pregnancy Group of the Italian Society of Nephrology

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