Influence of the structure of a bio-barrier forming agent on the stimuli-response and antimicrobial activity of a “smart” non-cytotoxic cotton fabric

Štular, Danaja; Jerman, Ivan; Simončić, Barbara; Grgić, Katia; Tomšič, Brigita

doi:10.1007/s10570-018-1992-z

Cited by 7 publications

(4 citation statements)

References 24 publications

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“…Specifically, smaller particles have greater specific surface area [6] and therefore exhibit a greater degree of swelling. On the other hand, regarding the influence of the β-CD inclusion on the temperature responsiveness of the PNCS hydrogel, it must be mentioned that β-CD hindered the moisture management properties compared to the pure PNCS hydrogel, which was well-studied and reported in our previous study [24]. At this point, it is important to note that the impaired moister management of the PNCS/CD hydrogel was reflected in its strong decrease of MC at 40 • C, showing that the presence of β-CD strongly affected moisture release.…”

Section: Responsive Propertiesmentioning

confidence: 69%

“…The hydrodynamic size was slowly decreased by gradually raising the temperature over the entire studied temperature range, showing the reduction of 66% in the particle size at the end of the experiment. Furthermore, comparison of the hydrodynamic particle size of the pure PNCS hydrogel that was determined in our previous research [24] to the hydrodynamic particle size of the PNCS/CD M1 hydrogel shows that at the same PN:CS ratio, the inclusion of β-CD into the hydrogel structure gave rise to an approximately 14% increase in the particle size. This finding unambiguously demonstrates the beneficial effect of the higher chitosan concentration in the formation of smaller and more stable particles for the PNCS/CD M2 hydrogel.…”

Section: Characterization Of the Hydrogelsmentioning

confidence: 70%

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Proactive Release of Antimicrobial Essential Oil from a “Smart” Cotton Fabric

et al. 2019

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Two temperature and pH responsive submicron hydrogels based on poly(N- methylenebisacrylamide), chitosan and β-cyclodextrines (PNCS/CD hydrogel) with varying poly(N-isopropylacrylamide) to chitosan ratios were synthesized according to a simplified procedure, reflecting improved stimuli responsive properties and excellent bio-barrier properties, granted by incorporated chitosan. Hydrogels were applied to cotton-cellulose fabric as active coatings. Subsequently, antimicrobially active savory essential oil (EO) was embedded into the hydrogels in order to develop temperature- and pH-responsive cotton-cellulose fabric with double antimicrobial activity, i.e., bio-barrier formation of chitosan along with the proactive release of savory EO at predetermined conditions. The influence of the hydrogels chemical composition on stimuli responsive and antibacterial properties were assessed. Both PNCS/CD hydrogels showed stimuli responsiveness along with controlled release of savory EO. The chemical composition of the hydrogels strongly influenced the size of the hydrogel particles, their temperature and pH responsiveness, and the bio-barrier forming activity. The increased concentration of chitosan resulted in superior overall stimuli responsiveness and excellent synergy between the antimicrobial activities of the hydrogel and released savory EO.

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Section: Responsive Propertiesmentioning

confidence: 69%

Section: Characterization Of the Hydrogelsmentioning

confidence: 70%

Proactive Release of Antimicrobial Essential Oil from a “Smart” Cotton Fabric

et al. 2019

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“…As a result of the large surface area of textile materials, there is a high risk of combustion when they come into contact with flames and ignite, as well as the attachment and growth of microbial pathogens and their transmission [ 38 , 39 ]. The antibacterial and antifungal properties are highly valuable functionalities, not only in terms of healthcare and hygiene concerns but also to increase the longevity of materials, while the antipathogenic performance must be non-toxic to humans and the environment [ 40 , 41 , 42 ]. In addition to the transmission of pathogens, which pose a serious threat to health, the growth of microorganisms leads to fabric deterioration, malodors, and discoloration [ 43 , 44 , 45 , 46 ].…”

Section: Introductionmentioning

confidence: 99%

New Insights into Antibacterial and Antifungal Properties, Cytotoxicity and Aquatic Ecotoxicity of Flame Retardant PA6/DOPO-Derivative Nanocomposite Textile Fibers

et al. 2021

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The aim of this study was to evaluate the antibacterial and antifungal activity, cytotoxicity, leaching, and ecotoxicity of novel flame retardant polyamide 6 (PA6) textile fibers developed by our research group. The textile fibers were produced by the incorporation of flame-retardant bridged 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) derivative (PHED) in the PA6 matrix during the in situ polymerization process at concentrations equal to 10 and 15 wt% (PA6/10PHED and PA6/15PHED, respectively). Whilst the nanodispersed PHED provided highly efficient flame retardancy, its biological activity led to excellent antibacterial activity against Escherichia coli and Staphylococcus aureus, as well as excellent antifungal activity against Aspergillus niger and Candida albicans. The results confirmed leaching of the PHED, but the tested leachates did not cause any measurable toxic effect to the duckweed Lemna minor. The in vitro cytotoxicity of the leached PHED from the PA6/15PHED sample was confirmed for human cells from adipose tissue in direct and prolonged contact. The targeted biological activity of the organophosphinate flame retardant could be beneficial for the development of PA6 textile materials with multifunctional properties and the low ecotoxicity profile, while the PHED’s leaching and cytotoxicity limit their application involving the washing processes and direct contact with the skin.

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“…Stimulus-responsive textiles have consequently emerged as an important category of functional materials, providing various applications as selfrepairing materials, textile sensors 9,10 and drug delivery materials. 11 Different stimulus have been employed to drive these intelligent textiles, including pH, 12 temperature, 13,14 and electric 15 and magnetic elds. 16,17 Microcapsule modications that seal various ingredients within small vectors that can easily be combined with textile bers have been widely studied in several elds on the basis of their controlled release and delivery properties.…”

Section: Introductionmentioning

confidence: 99%