Influence of the Type and Degree of Left Ventricular Hypertrophy on the Prevalence of Ventricular Arrhythmias in Patients with Hypertensive Heart Disease

Abstract

: There was no correlation between type of LVH and prevalence of VA. The severity of hypertrophy contributes more to a greater prevalence of VA than the LVH pattern. The combination of severe degree and concentric type carries the greatest cardiovascular risk.

Influence of Patern and Degree of Left Ventricular Hypertrophy on Cardiac Arrhythmias

“…Ejection fraction (EF) is most often very good (>60%). The values of mean LVMI, and in both genders are much higher than normal values (>170 g/m 2 ) Concentric LVH is the most frequent (63% in [26]), which is not in agreement with some earlier investigations [28]. Eccentric LVH, usually of a mild degree, is more frequently observed in male patients.…”

“…The majority subjects are physically inactive with elevated values of lipids and urea in serum [26]. Echocardiographic measurements confirme anthropological differences between genders [27].…”

“…During Holter monitoring this percentage increased to over 40% of patients, and during the stress test it increased by additional 7,4% (in proportion to heart rate and blood pressure). Ventricular tachycardia can be found in 7-18% [26]. Some authors [24] found that concentric hypertrophy carries the greatest risk, and the eccentric a moderate risk of death and of CV complications.…”

Influence of the left ventricular types on QT intervals in hypertensive patients

“…Such patients are difficult to find in larger number because in urban areas they are recognized and treated rather early before severe LVH has managed to develop. Moreover, it should also be taken into account that these patients, except for hypertensive cardiomyopathy, should have no other diseases ( 12 ). Consequently, not many articles investigating this correlation have been published in the literature ( 1 , 8 ).…”

“…Patients with diabetes mellitus, alcoholics (exclusion was based on their medical history, clinical status and laboratory findings), patients with mental disorders, those overusing non-antihypertensive drugs, patients with malignant or accelerated hypertension and those that had suffered a stroke in the previous six months were also excluded. Patients with cancer, abnormal electrolytes, anemia, cardiopulmonary diseases (chronic lung diseases, sleep apnea), serum creatinine >140 µmol/L and abnormal thyroid function, those taking medication that can increase QTc (antiarrhythmics; anti-biotics: macrolides, quinolones; some antipsychotics and anti-depressants) were also ruled out ( 12 ). Echocardiography confirmed the diagnosis of LVH in the remaining 194 patients.…”