Influence of the Vibration Impact Mode on the Spontaneous Chemiluminescence of Aqueous Protein Solutions

Astashev, Maxim E.; Serov, Dmitriy A.; Sarimov, Ruslan M.; Gudkov, Sergey V.

doi:10.3103/s1541308x23030020

Cited by 7 publications

(7 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Stirring the treated water had a specific effect on the protein, similar to what happened when the protein solution was directly treated with a magnetic field. The magnetic field does not affect the chemiluminescence parameters of water but changes the intensity and standard deviation of the chemiluminescence intensity of aqueous solutions of IgG [138]. The severity of the effect depends both on the frequency of the applied magnetic field and on the protein concentration.…”

Section: Effects Of Hmc On Solutionsmentioning

confidence: 98%

See 1 more Smart Citation

Hypomagnetic Conditions and Their Biological Action (Review)

Sarimov,

Serov,

Gudkov

2023

Biology

View full text Add to dashboard Cite

The geomagnetic field plays an important role in the existence of life on Earth. The study of the biological effects of (hypomagnetic conditions) HMC is an important task in magnetobiology. The fundamental importance is expanding and clarifying knowledge about the mechanisms of magnetic field interaction with living systems. The applied significance is improving the training of astronauts for long-term space expeditions. This review describes the effects of HMC on animals and plants, manifested at the cellular and organismal levels. General information is given about the probable mechanisms of HMC and geomagnetic field action on living systems. The main experimental approaches are described. We attempted to systematize quantitative data from various studies and identify general dependencies of the magnetobiology effects’ value on HMC characteristics (induction, exposure duration) and the biological parameter under study. The most pronounced effects were found at the cellular level compared to the organismal level. Gene expression and protein activity appeared to be the most sensitive to HMC among the molecular cellular processes. The nervous system was found to be the most sensitive in the case of the organism level. The review may be of interest to biologists, physicians, physicists, and specialists in interdisciplinary fields.

show abstract

Section: Effects Of Hmc On Solutionsmentioning

confidence: 98%

“…Another parameter that is often used to record the effects of MFs is the luminescence of water and aqueous solutions of proteins [138,139]. Altered magnetic fields (3.7 Hz frequency and induction of 0.04 µT, induction of constant MF, 42 µT) increased the luminescence intensity several times during 2-4 h of treatment [139].…”

Section: Effects Of Hmc On Solutionsmentioning

confidence: 99%

Hypomagnetic Conditions and Their Biological Action (Review)

Sarimov,

Serov,

Gudkov

2023

Biology

View full text Add to dashboard Cite

show abstract

“…The effects TVMFs can also manifest themselves at the level of water and aqueous solutions of proteins [214,215]. In particular, a TVMF with a frequency of 50 Hz and an induction of 50 µT causes an increase in the spontaneous chemiluminescence of aqueous solutions of immunoglobulins [216]. There is evidence in the literature about the ability of weak EMFs to influence the redistribution of charges in protein molecules and, as a consequence, change their conformation [217].…”

Section: Effects At the Molecular-cellular Level (Laboratory Studies)mentioning

confidence: 99%

Biological Effects of Magnetic Storms and ELF Magnetic Fields

Sarimov,

Serov,

Gudkov

2023

Biology

View full text Add to dashboard Cite

Magnetic fields are a constant and essential part of our environment. The main components of ambient magnetic fields are the constant part of the geomagnetic field, its fluctuations caused by magnetic storms, and man-made magnetic fields. These fields refer to extremely-low-frequency (<1 kHz) magnetic fields (ELF-MFs). Since the 1980s, a huge amount of data has been accumulated on the biological effects of magnetic fields, in particular ELF-MFs. However, a unified picture of the patterns of action of magnetic fields has not been formed. Even though a unified mechanism has not yet been generally accepted, several theories have been proposed. In this review, we attempted to take a new approach to analyzing the quantitative data on the effects of ELF-MFs to identify new potential areas for research. This review provides general descriptions of the main effects of magnetic storms and anthropogenic fields on living organisms (molecular–cellular level and whole organism) and a brief description of the main mechanisms of magnetic field effects on living organisms. This review may be of interest to specialists in the fields of biology, physics, medicine, and other interdisciplinary areas.

show abstract

“…When conducting experiments, influences similar to those used on technological lines of pharmaceutical production were used. A special device was developed for implementing mechanical effects with different frequencies and amplitudes on samples (mixing in a turbulent flow in the vertical direction), described in detail in [30]. A vertical drilling machine, PBD 40 (Bosch, Gerlingen, Germany), with a lever for performing vertical vibrations was used as the basis of the device.…”

Section: Mechanical Vibration Effectmentioning

confidence: 99%

Possible Approaches to Studying the Influence of Magnetic Fields and Mechanical Effects on the Physicochemical Properties of Aqueous IgG Colloids

Nagaev,

Molkova,

Pustovoy

et al. 2023

Applied Sciences

View full text Add to dashboard Cite

The influence of various mechanical influences (transfusion, stirring, vibration, shaking, etc.) and magnetic installations (used in the application of spin chemistry methods) on colloidal solutions of protein and water, which are often used in pharmaceutical production, was studied. It has been shown that when mechanical influences are applied, physical and chemical properties of water and aqueous colloids of the IgG protein are changed. Magnetic fields do not have a significant effect on water; however, variation in a number of physical and chemical characteristics is observed in protein colloids. Moreover, the effect after exposure to magnetic fields with a frequency of 8 Hz is higher compared to the effect after exposure to magnetic fields with a frequency of 50 Hz. This effect persists even at extremely low concentrations of IgG protein molecules. The measurement system proposed in this work makes it possible to monitor the state of protein molecules in a non-invasive mode. In the future, optical and potentiometric methods built into flow systems can be used at all stages of the production of protein pharmaceuticals.

show abstract

Influence of the Vibration Impact Mode on the Spontaneous Chemiluminescence of Aqueous Protein Solutions

Cited by 7 publications

References 42 publications

Hypomagnetic Conditions and Their Biological Action (Review)

Hypomagnetic Conditions and Their Biological Action (Review)

Biological Effects of Magnetic Storms and ELF Magnetic Fields

Possible Approaches to Studying the Influence of Magnetic Fields and Mechanical Effects on the Physicochemical Properties of Aqueous IgG Colloids

Contact Info

Product

Resources

About