The natural draft dry cooling tower is a crucial equipment for thermal power plants in arid regions due to its water-saving capabilities and low energy consumption. However, crosswind conditions can significantly affect the operational performance of NDDCTs, making it crucial to understand their operation characteristics under such conditions. This study uses CFD simulation to analyze the operational properties of an NDDCT group with various crosswind conditions, examining key factors such as flow, temperature, velocity fields, and the interplay between towers. When the crosswind has an angle with the symmetry axis of the NDDCTs group, the NDDCTs have better performance. NDDCTs have the best performance when the angle is 30 °. The findings offer critical theoretical insights and data support for the design and optimization of NDDCT groups, with significant engineering and academic implications.