“…For the Jardins site, which is our reference clean site, significant reduction of phagocytosis was also obtained with the three metals in clams collected in upper shore. However, the suppression was observed at higher metal concentrations (10 - immunocompetence is altered by pollution such as Hg, but this response could be also modulated by environmental stresses such as temperature, cyclic or tidal exposure to air 9 and pathogens. 1,10 In the present study, we wanted to evaluate the impact of exposure to air, during tidal events, on the sensitivity of hemocytes to metal exposures.…”