Influence of Tube-Spacer on Aerosol Efficacy

Spicer, John; Cayton, R.M.; Frame, Madeline H.; Winsey, N J

doi:10.1016/s0140-6736(80)92505-2

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1982

1991

Publication Types

Select...

Article4

Book2

Relationship

Self Cite0

Independent6

Authors

Journals

Cited by 15 publications

(1 citation statement)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Increasing the volume in the chamber increases the time required for treatment; this factor can be offset by increasing the flow rate. A flow rate of [6][7][8] Umin is recommended. The output of ultrasonic nebulizers is considerably higher than jet nebulizers; however, droplet coagulation is also more likely to occur.…”

mentioning

confidence: 99%

Aerosol Deposition and Delivery of Therapeutic Aerosols

Hilman¹

1991

Journal of Asthma

View full text Add to dashboard Cite

mentioning

confidence: 99%

Aerosol Deposition and Delivery of Therapeutic Aerosols

Hilman¹

1991

Journal of Asthma

View full text Add to dashboard Cite

Bronchodilator effect of fenoterol and ipratropium bromide in infants with acute wheezing: Use of MDI with a spacer device

Mallol¹,

Barrueto²,

Girardi

et al. 1987

Pediatric Pulmonology

View full text Add to dashboard Cite

Twenty-eight infants admitted to Exequiel González Cortes Children's Hospital because of acute wheezing (AW) were randomly assigned to three study groups. Fenoterol (FNT), ipratropium bromide (IB), and placebo were administered respectively to children in the different groups by means of metered dose inhalers (MDI) with spacers, using doses of 3 puffs every hour, for 4 hours. The degree of bronchial obstruction was assessed clinically and scored with the single-blind method every hour prior to each treatment. The criterion of a bronchodilator effect was a significant decrease in the degree of bronchial obstruction at subsequent scorings. The scores of the three groups were compared using the Student's t test for matched samples. The same test was also applied to the independent samples for determining the superiority of one treatment, FNT or IB, over the other. The results indicated a significant decrease in the scores of the groups receiving FNT and IB (P less than 0.05); this did not occur in the group in which placebo was used. FNT produced a more rapid and sustained effect than IB (P less than 0.05). Significant bronchodilator effect was obtained in infants with AW when repeated doses of FNT or IB were administered with MDI and spacers. This effect was significantly greater in the group treated with FNT.

show abstract

Besondere Therapieformen

Matthys¹

1988

Pneumologie

View full text Add to dashboard Cite

Influence of Tube-Spacer on Aerosol Efficacy

Cited by 15 publications

References 2 publications

Aerosol Deposition and Delivery of Therapeutic Aerosols

Aerosol Deposition and Delivery of Therapeutic Aerosols

Bronchodilator effect of fenoterol and ipratropium bromide in infants with acute wheezing: Use of MDI with a spacer device

Besondere Therapieformen

Contact Info

Product

Resources

About