This paper analyzes the impact of the industrial structure(IS) change of smart grid(SG) on energy consumption(EC). The supporting system of SG and the main control signals in different stages are analyzed, and the general law of EC and energy economic effect coefficient are discussed; Analysis algorithm of the impact of IS change on EC, and then analyzes the impact of IS change of SG on energy efficiency; Through statistical testing, decomposition of energy intensity and analysis of carbon emission characteristics of regional intelligent distribution network in recent 10 years, it is concluded that the change of IS of intelligent distribution network has a great impact on EC. SG uses intelligent interaction to promote real-time communication between supply and demand sides, so as to improve power efficiency and save EC.