This study investigates the impact of equivalent salt deposit density (ESDD) and non-soluble deposit density (NSDD) on the flashover voltage of 150 kV transmission line insulators. The high flashover rates on the Koto Panjang-Payakumbuh transmission line in Indonesia, particularly in hilly regions, indicate that contaminants significantly affect the insulator’s performance. The research utilizes the Anderson method and experimental data to analyze flashover voltage variations due to different contamination levels. Results show that the highest flashover voltage was observed at NSDD of 0.8401 mg/cm2 with values of 395.44 kV (Anderson) and 346 kV (experiment), and the lowest at NSDD of 1.0151 mg/cm2 with values of 394.40 kV (Anderson) and 341 kV (experiment). For ESDD, the highest voltage was at 160.8 mg/cm2 with 395.44 kV (Anderson) and 341 kV (experiment), and the lowest at 258.6 mg/cm2 with 394.40 kV (Anderson) and 341 kV (experiment). The strong correlation between flashover voltage and contaminant levels emphasizes the need for effective monitoring and control of contamination on insulators to improve reliability in power transmission systems.