2002
DOI: 10.1016/s0899-9007(01)00784-5
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Influences of soybean oil emulsion on stress response and cell-mediated immune function in moderately or severely stressed patients

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Cited by 96 publications
(70 citation statements)
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“…We previously showed that insulin resistance with IL was due to impaired insulin signaling and was associated with increased hepatic inflammation, and thus it was notable in the current study that we found that hepatic Il-6 expression was highest in IL versus OV and SL piglets (40). The explanation for lower hepatic inflammation could be due to the anti-inflammatory and anti-oxidant effects associated with higher liver enrichment of n-3 PUFAs, DHA, and EPA, as well as -tocopherol in the OV and SL versus IL piglets (24,41,42).…”
Section: Discussionmentioning
confidence: 50%
“…We previously showed that insulin resistance with IL was due to impaired insulin signaling and was associated with increased hepatic inflammation, and thus it was notable in the current study that we found that hepatic Il-6 expression was highest in IL versus OV and SL piglets (40). The explanation for lower hepatic inflammation could be due to the anti-inflammatory and anti-oxidant effects associated with higher liver enrichment of n-3 PUFAs, DHA, and EPA, as well as -tocopherol in the OV and SL versus IL piglets (24,41,42).…”
Section: Discussionmentioning
confidence: 50%
“…[12][13][14][15] The nutrient infusion was designed to approximate the composition of a normal diet, with 16% of the energy coming from protein, 52% from carbohydrate, and 32% from fat, and provided a steady-state availability of nutrients with an osmolarity (≤700 mOsm/L) acceptable for peripheral administration. Glucose infusion rate was 3.3 mg/kg/min and non-protein calorie to nitrogen ratio was 140.…”
Section: Nutrient Infusionmentioning
confidence: 99%
“…Studies have shown that the n-6 PUFA linoleic acid may have suppressive effects on cell-mediated immunity [9,10]. In contrast, oleic acid has been found to induce few or no immunomodulatory effects.…”
Section: Introductionmentioning
confidence: 99%