Influencing medication adherence among women with AIDS

Jones, Deborah L.; Ishii, Mary; LaPerriere, A.; Stanley, Heidi; Antoni, Mike; Ironson, Gail; Schneiderman, Neil; Splunteren, F. Van; Cassells, Andrea; Alexander, Kamila A.; Gousse, Yolene; Vaughn, Anita; Brondolo, Elizabeth; Tobin, Jonathan N.; Weiss, Steve

doi:10.1080/0954012031000134700

Cited by 61 publications

(44 citation statements)

References 19 publications

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“…The program was subsequently adapted to include all women living with HIV and translated linguistically and culturally from English into Spanish and Creole. A healthy lifestyle program targeting multiple health risk behaviors was incorporated, and the program was found to reduce stress/ distress and depression and anxiety, decrease HIV viral load, and enhance coping and self-efficacy, while improving health status and quality of life [15][16][17][18][19][20][21][22]. Between 2007 and 2011, a translation of this evidence-Implications Practice: The Stress Management and Relaxation Training/Expressive-Supportive Therapy Women's Program (SWP) can be implemented in community-based practice, utilizing existing community health center staff with diverse education levels and training backgrounds, and achieves improved health outcomes in women living with HIV.…”

Section: Introductionmentioning

confidence: 99%

Translation of a comprehensive health behavior intervention for women living with HIV: the SMART/EST Women's Program

Jones

López

Simons

et al. 2013

Behav. Med. Pract. Policy Res.

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Translation of behavioral interventions into community settings for people living with HIV/AIDS can decrease the risk of comorbid conditions. This study was designed to determine whether a multiple health behavior intervention for women with HIV/AIDS could be effectively translated into community health centers (CHCs), delivered by CHC primary care staff. Health Resources and Services Administration-supported CHCs in Miami, FL, and the New York metropolitan area participated. Six health behavior domains were assessed at baseline, 6 months, and 12 months postintervention: nutrition, physical activity, sexual risk behavior, alcohol use, drug use, and tobacco use. Behavioral outcomes were compared between research staff-led and CHC staff-led intervention groups. Research staff and CHC staff outcomes were similar for the majority of outcomes. Results indicate that complex, multicomponent behavioral interventions can be translated into community-based settings with existing CHC staff and can produce clinical effects similar to those achieved by research staff.

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Section: Introductionmentioning

confidence: 99%

Translation of a comprehensive health behavior intervention for women living with HIV: the SMART/EST Women's Program

Jones

López

Simons

et al. 2013

Behav. Med. Pract. Policy Res.

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“…Several publications from three federally funded studies conducted by UMMSM and CDN over a 10-year period confirmed the evidence base of the program [3][4][5][6][7][8][9][10][11][12][13][14][15].…”

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confidence: 86%

Translating evidence-based interventions from research to practice: challenges and lessons learned

Lopez-Patton

Weiss

Diaz-Gloster

2015

Behav. Med. Pract. Policy Res.

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Despite the increasing popularity of translation research, few studies have described the process and challenges involved in implementing a translation study. The main objective was to determine whether a multi-component group behavioral intervention could be successfully translated from an academic setting into the community health system of federally qualified health centers (FQHCs) funded by the Health Resources and Services Administration (HRSA) in Miami, NY, and NJ. Key challenges and Blessons learned^from the dissemination and implementation process for the SMART/EST (Stress Management And Relaxation Training/Emotional Supportive Therapy) Women's Project (SWP) III in low-resource primary care settings are described. The Reach Effectiveness Adoption Implementation Maintenance (RE-AIM) model served as the theoretical framework for the translation of the study. This study outlines several essential factors related to Glasgow's RE-AIM model that need to be considered in order to accomplish successful translation of evidence-based interventions from traditional academia to Breal-world^community health center settings. KeywordsBehavioral interventions, Implementation of translation research, Challenges in translation, SMART/EST Women's Project Until recently, most health research consisted of formulating innovative approaches to the prevention and/or control of a medical condition; preparing (successful) applications for federal support; demonstrating the efficacy of an untested procedure, compound, or strategy; and publishing one's findings in one or more scientific journals. Today, this still may be Bnecessary,^but Bnot sufficient^to warrant the support of the major health research funding agencies. As Russell Glasgow's Reach Effectiveness Adoption Implementation Maintenance (RE-AIM) model [1, 2] so cogently outlines, addressing the Beffectiveness^and Bsustainability^of clinical findings may be equally or even more important than the findings themselves, if research is to have a meaningful impact on national and global public health. Thus, the scientific community has taken on the challenge of demonstrating the utility of research findings through Btranslational^re-search, which examines methods to successfully implement and disseminate academic research findings into clinical and public health service settings. This paper will share with the reader some of the key challenges and Blessons learned^from experiences of this research team with the dissemination and implementation process for a multi-component group behavioral intervention in low-resource primary care settings.The SMART/EST (Stress Management And Relaxation Training/Emotional Supportive Therapy) Women's Project (SWP) is an evidence-based behavioral intervention designed to enhance the overall quality of life and health status of culturally diverse, disadvantaged women living with HIV/AIDS [3,4] Policy: Support in the form of government funding for community health center training can maximize the success, impact, and scope of translation re...

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“…12 The scarcity of validated ART adherence questions in SSA is all the more surprising because our understanding of ART adherence in the region is largely based on patient responses to adherence questions, 19 and interventions to increase adherence in routine care are commonly evaluated using adherence questions as outcome measures. [20][21][22][23] Some studies outside of SSA have demonstrated significant associations between self-reported adherence and viral load 13 and antiretroviral (ARV) plasma concentrations. 26 However, other studies found that self-reported adherence was only weakly correlated with viral suppression and antiretroviral drug concentrations.…”

Section: Introductionmentioning

confidence: 99%

Validating Five Questions of Antiretroviral Nonadherence in a Public-Sector Treatment Program in Rural South Africa

Chaiyachati

Hirschhorn

Tanser

et al. 2011

AIDS Patient Care and STDs

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Simple questions are the most commonly used measures of antiretroviral treatment (ART) adherence in subSaharan Africa (SSA), but rarely validated. We administered five adherence questions in a public-sector primary care clinic in rural South Africa: 7-day recall of missed doses, 7-day recall of late doses, a six-level Likert item, a 30-day visual analogue scale of the proportion of doses missed, and recall of the time when an ART dose was last missed. We estimated question sensitivity and specificity in detecting immunologic (or virologic) failure assessed within 45 days of the adherence question date. Of 165 individuals, 7% had immunologic failure; 137 individuals had viral loads with 9% failure detected. The Likert item performed best for immunologic failure with sensitivity/specificity of 100%/5% (when defining nonadherence as self-reported adherence less than ''excellent''), 42%/55% (less than ''very good''), and 25%/95% (less than ''good''). The remaining questions had sensitivities 17%, even when the least strict cutoffs defined nonadherence. When we stratified the analysis by gender, age, or education, question performance was not substantially better in any of the subsamples in comparison to the total sample. Five commonly used adherence questions performed poorly in identifying patients with treatment failure in a public-sector ART program in SSA. Valid adherence measurement instruments are urgently required to identify patients needing treatment support and those most at risk of treatment failure. Available estimates of ART adherence in SSA are mostly based on studies using adherence questions. It is thus unlikely that our understanding of ART adherence in the region is correct.

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Influencing medication adherence among women with AIDS

Cited by 61 publications

References 19 publications

Translation of a comprehensive health behavior intervention for women living with HIV: the SMART/EST Women's Program

Translation of a comprehensive health behavior intervention for women living with HIV: the SMART/EST Women's Program

Translating evidence-based interventions from research to practice: challenges and lessons learned

Validating Five Questions of Antiretroviral Nonadherence in a Public-Sector Treatment Program in Rural South Africa

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