Influenza A-associated Rhabdomyolysis with Acute Renal Failure

Dworschak, A.; Wiebe, Britt Marie; Pohlmann, Ulrike; Ehlen, Michael; Scholer-Everts, R.; Bartmann, Peter

doi:10.1055/s-2007-1022569

Cited by 6 publications

(5 citation statements)

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“…4 On the other hand, rhabdomyolytic episodes in healthy individuals have also been reported in association with some viral infections. [7][8][9] Among 42 cases of virus-induced rhabdomyolysis, influenza virus was the most common cause and coxsackie virus tends to be the next most common; however, an association with human parvovirus B19 infection has never been reported. 7 Viruses belonging to the family Picornaviridae such as coxsackie virus have an affinity for muscle cells.…”

Section: Discussionmentioning

confidence: 99%

Rhabdomyolysis Associated With Human Parvovirus B19 Infection in a Patient With Fukuyama-Type Congenital Muscular Dystrophy

et al. 2013

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Patients with Fukuyama-type congenital muscular dystrophy sometimes experience transient exacerbations of muscle weakness. We took care of a 9-year-old boy with Fukuyama-type congenital muscular dystrophy who presented with acute respiratory failure and decreased exercise ability with marked elevation of serum creatine kinase indicating rhabdomyolysis. At that time, his younger sister suffered from erythema infectiosum. Although he had no particular symptoms, he was tested and proven to have acute human parvovirus B19 infection based on detection of anti-B19 IgM and parvovirus B19 DNA in his serum. His acute rhabdomyolysis was possibly triggered by human parvovirus B19 infection.

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Section: Discussionmentioning

confidence: 99%

Rhabdomyolysis Associated With Human Parvovirus B19 Infection in a Patient With Fukuyama-Type Congenital Muscular Dystrophy

et al. 2013

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“…Rhabdomyolysis after influenza virus infection has been recently reported [ 1 - 3 ]; however, compartment syndrome caused by swelling of a massive muscular compartment is an uncommon complication. In addition, hemoconcentration, hypoalbuminemia, and hypovolemic shock due to a marked shift of plasma are not the features of simple rhabdomyolysis but those of systemic capillary leak syndrome (SCLS) [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Systemic capillary leak syndrome induced by influenza type A infection

et al. 2014

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A 42-year-old man visited the emergency department complaining of lower extremity swelling and myalgia. His influenza A antigen test was positive, and he was admitted for supportive care of severe myalgia. On the first hospital day, the swelling in his lower legs was aggravated with intolerable pain, and his creatine phosphokinase and hemoglobin levels were elevated. He was treated with massive hydration, albumin replacement, continuous venovenous hemofiltration, phlebotomy, and oseltamivir. The swelling and pain in his extremities were decreased without renal dysfunction, even though peripheral neuropathy and muscular complication persisted. Systemic capillary leak syndrome is a rare but life-threatening condition. The diagnosis is made clinically based on a classic triad of hypotension, hypoalbuminemia, and hemoconcentration. In our case, the influenza A infection was related to the capillary leakage.

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“…Influenza viruses affect the musculoskeletal system most commonly in the form of myositis, which may range from benign myalgias to life threatening rhabdomyolysis [ 1 ]. Although reactive arthritis has been described in adults after influenza immunization [ 2 - 4 ], arthritis associated with influenza virus infection in humans has, to our knowledge, not been documented in the international literature, particularly not in pediatric patients.…”

Section: Introductionmentioning

confidence: 99%