Influenza and pertussis vaccination coverage in pregnant women

Laenen, Jolien; Roelants, Mathieu; Devlieger, Roland; Vandermeulen, Corinne

doi:10.1016/j.vaccine.2015.03.020

Cited by 107 publications

(85 citation statements)

References 34 publications

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“…For influenza vaccine, lack of a strong and unequivocal recommendation by healthcare professionals, government, and advisory bodies also contributed to decreased vaccine uptake among some populations. 28,[32][33][34]41,42,46,51,52 Many of the facilitators associated with increased vaccine uptake were the opposite of the barriers identified. High level of vaccine knowledge, 28,49,53,54 perceived vaccine effectiveness 50 and benefit, 41 increased perception of disease severity, 39,45 and feeling personal susceptibility 42,45,47,50 were predictive of improved vaccine uptake during pregnancy.…”

Section: Factors Related To Pregnant Womenmentioning

confidence: 99%

“…28,29,[34][35][36][37][38][39][40][41] Most women identified safety concerns such as side effects as the greatest barrier to immunization during pregnancy. [29][30][31][32][35][36][37][38]42,43,45,46 While women were concerned about their own safety 25,30,34,37,[44][45][46]51,52 or prior adverse events with the vaccine, 46,47 safety concerns for the fetus and newborn were paramount. 22,25,30,31,34,39,[44][45][46]51,52 Doubt about the effectiveness of the vaccine was particularly noted with influenza vaccine.…”

Section: Factors Related To Pregnant Womenmentioning

confidence: 99%

“…[29][30][31][32][35][36][37][38]42,43,45,46 While women were concerned about their own safety 25,30,34,37,[44][45][46]51,52 or prior adverse events with the vaccine, 46,47 safety concerns for the fetus and newborn were paramount. 22,25,30,31,34,39,[44][45][46]51,52 Doubt about the effectiveness of the vaccine was particularly noted with influenza vaccine. 22,25,32,34,35 General mistrust of vaccinations 37 was mentioned in studies related to influenza, 29 pertussis, 30 and group B Streptococcus.…”

Section: Factors Related To Pregnant Womenmentioning

confidence: 99%

“…47,50 The desire to protect the fetus/infant and oneself from disease was a strong predictor of immunization. 22,23,29,34,42,46,55,56 Most consistently, having the vaccine recommended AND offered by their healthcare provider [21][22][23]25,28,29,[31][32][33][34][37][38][39][40]42,45,46,50,[54][55][56][57][58][59][60] and trusting the recommendations 47 were identified most frequently as important in increasing vaccine uptake. For influenza vaccine, prior vaccination of oneself 25,28,34,45,46,53,60 or one's partner 59 in previous years was a strong predictor of acceptance of vaccination during pregnancy.…”

Section: Factors Related To Pregnant Womenmentioning

confidence: 99%

“…22,25,32,34,35 Protect baby and self from disease. 22,23,29,34,42,46,55,56 Text messaging with general pregnancy health and vaccination information, and appointment reminders. 81,82 Lack of vaccine knowledge.…”

Section: Factors Related To Healthcare Providers Recommending Vaccinesmentioning

confidence: 99%

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Improving rates of maternal immunization: Challenges and opportunities

MacDougall

Halperin

2015

Human Vaccines & Immunotherapeutics

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Objectives: An increasing number of vaccines are recommended or are being developed for use during pregnancy to protect women, fetuses, and/or newborns. For vaccines that are already recommended, vaccine uptake is variable and well below desired target. We reviewed the literature related to factors that affect a healthcare provider's recommendation and a woman's willingness to be vaccinated during pregnancy. Design: A scoping review of published literature from 2005 to 2015 was undertaken and all relevant articles were abstracted, summarized, and organized thematically. Results: Barriers and facilitators were identified that either decreased or increased the likelihood of a healthcare provider offering and a pregnant woman accepting vaccination during pregnancy. Concern about the safety of vaccines given during pregnancy was the most often cited barrier among both the public and healthcare providers. Other barriers included doubt about the effectiveness of the vaccine, lack of knowledge about the burden of disease, and not feeling oneself to be at risk of the infection. Major facilitators for maternal immunization included specific safety information about the vaccine in pregnant women, strong national recommendations, and healthcare providers who both recommended and provided the vaccine to their patients. Systems barriers such as inadequate facilities and staffing, vaccine purchase and storage, and reimbursement for vaccination were also cited. Evidence-based interventions were few, and included text messaging reminders, chart reminders, and standing orders. Conclusions: In order to have an effective vaccination program, improvements in the uptake of recommended vaccines during pregnancy are needed. A maternal immunization platform is required that normalizes vaccination practice among obstetrical care providers and is supported by basic and continuing education, communication strategy, and a broad range of research.

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Section: Factors Related To Pregnant Womenmentioning

confidence: 99%

Section: Factors Related To Pregnant Womenmentioning

confidence: 99%

Section: Factors Related To Pregnant Womenmentioning

confidence: 99%

Section: Factors Related To Pregnant Womenmentioning

confidence: 99%

Section: Factors Related To Healthcare Providers Recommending Vaccinesmentioning

confidence: 99%

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Improving rates of maternal immunization: Challenges and opportunities

MacDougall

Halperin

2015

Human Vaccines & Immunotherapeutics

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Maternal awareness, acceptability and willingness towards respiratory syncytial virus (RSV) vaccination during pregnancy in Ireland

McCormack,

Thompson,

Nolan

et al. 2024

Immunity Inflam & Disease

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BackgroundRespiratory syncytial virus (RSV) is the world's leading cause of viral acute lower respiratory infections (ALRI) in infants. WHO has identified maternal RSV vaccination a priority and candidate vaccines are in development; however, vaccine hesitancy remains an impediment to successful implementation of maternal immunization. This study, the largest antenatal survey conducted to‐date, aimed to examine maternal RSV awareness, likely acceptance of RSV vaccination in pregnancy, and attitudes to maternal vaccination.MethodsPregnant women of all gestations attending antenatal clinic of a university maternity hospital in Ireland were invited to participate. An information leaflet provided, consent obtained, and survey administered examining RSV awareness, willingness to avail of antenatal RSV vaccination, factors influencing acceptability and preferred sources of assistance. Research Ethics Committee (REC) approval obtained, and general data protection regulation (GDPR) guidelines followed.Results528 women completed the survey. A large proportion (75.6%) had never heard of RSV, yet 48.5% would still avail of a vaccine, 45.8% were undecided and only 5.3% would not. The main factor making vaccination acceptable to women (76.4%) was that it protects their infant from illness (p < .001, CV 0.336 for association with acceptance) and general practitioner (GP) was the preferred guidance source in decision‐making (57.7%).ConclusionsDespite low levels of maternal awareness of RSV, pregnant women in Ireland are open to availing of antenatal vaccination. Maternal immunization strategies need to focus on infant's protection from RSV‐associated ALRI along with vaccine safety, and build on an interdisciplinary collaboration of maternal, neonatal, primary care and public health services.

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Understanding Barriers and Facilitators to Maternal Immunization: A Systematic Narrative Synthesis of the Published Literature

Geoghegan

Shuster

Butler

et al. 2022

Matern Child Health J

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Introduction Vaccines are being developed against Group B Streptococcus and respiratory syncytial virus. These vaccines are designed to be given to pregnant women to protect infants; thus, their success depends on uptake in this population. Maternal immunization programs have struggled to achieve target coverage rates. This systematic narrative synthesis aims to define the most important barriers and facilitators for maternal immunization and to identify priority areas for future research. Methods A search strategy was developed in Medline and adapted according to the requirements of additional search engines. Two reviewers independently reviewed the studies, using pre-specified inclusion and exclusion criteria. Results sections of included studies were coded, and thematic analysis was used to identify prominent themes. Results 321 studies were included in the final review. Most studies came from North America (37%), Europe (26%) or East Asia, Australia and New Zealand (22%). Low-and middle-income countries were under-represented. Five percent of studies came from Sub-Saharan Africa, and 2% came from South Asia. The prominent factors impacting maternal immunization were provider recommendation, perceived risks and benefits of maternal vaccines for the infant, race, birthplace, and access to healthcare. Few studies explored reasons behind racial and socioeconomic disparities in maternal immunization rates. Discussion A strong provider recommendation, equitable access to prenatal care and messaging that focuses on vaccine safety and infant benefits emerged as the key components for optimising vaccine uptake among pregnant women. Research among healthcare providers, minority groups and in low- and-middle-income countries was lacking. In anticipation of the expansion of maternal immunization programmes, focused research is needed to address these gaps and inform a successful public health strategy. Supplementary Information The online version contains supplementary material available at 10.1007/s10995-022-03508-0.

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Influenza and pertussis vaccination coverage in pregnant women

Abstract: Incomplete documentation is the most important barrier in determining the vaccination status of pregnant women. Immunization during pregnancy needs further integration through vaccination campaigns aimed at both health care providers and pregnant women.

Cited by 107 publications

References 34 publications

Improving rates of maternal immunization: Challenges and opportunities

Improving rates of maternal immunization: Challenges and opportunities

Maternal awareness, acceptability and willingness towards respiratory syncytial virus (RSV) vaccination during pregnancy in Ireland

Understanding Barriers and Facilitators to Maternal Immunization: A Systematic Narrative Synthesis of the Published Literature

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